Xi`an Eastling Biotech Co., Ltd.
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City: Xi'an city
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CAS NO.969-33-5
98%(500-1000)Kilogram98%(100-500)Metric Ton
| Molecular Formula | C21H22ClN |
| Molar Mass | 323.86 |
| Melting Point | 254-256.5 °C(Solv: ethanol (64-17-5); ethyl ether (60-29-7)) |
| Solubility | ethanol: soluble |
| Color | Crystals from EtOH/Et2O |
| Storage Condition | Inert atmosphere,Room Temperature |
| Use | Cyproheptadine HCl is the Cyproheptadine hydrochloride form and is a histamine receptor antagonist that acts on the 5-HT2 receptor with an IC50 of 0.6 nM. |
| Introduction | cyproheptadine hydrochloride, also known as diphenylcycloheptadine, metapantin, ethylphenylcycloheptadine, A hexahydropyridine antihistamine that competes with histamine released from tissues for H1 receptors on effector cells, thereby preventing the onset of allergic reactions, relieve histamine induced spasmolysis and hyperemia, the goods have a strong H1 receptor antagonism, antihistamine effect than chlorpheniramine, promethazine strong. Mild to moderate anti-serotonin and anti-cholinergic effects. In addition, there is the role of stimulating appetite, after a certain period of time visible weight gain. |
| properties | cyproheptadine hydrochloride is a white or yellowish crystalline powder, almost odorless and slightly bitter in taste. Soluble in methanol, dissolved in chloroform, slightly soluble in ethanol, slightly soluble in water, almost insoluble in ether. |
| Clinical application | clinically cyproheptadine hydrochloride is mainly used for acute and chronic urticaria (especially cold urticaria has good effect), papular urticaria, angioedema, allergic eczema, contact dermatitis, food allergy, drug allergy, allergic rhinitis, hay fever, allergic conjunctivitis, insect sting allergy and migraine. It has a certain therapeutic effect on bronchial asthma. Can be used for Cushing's syndrome, acromegaly adjuvant therapy. It can also be used as an appetite enhancer for anorexia nervosa. Treatment of acanthosis nigricans and prevention of necrotizing pyoderma have been reported. |
| side effects | 1. Drowsiness or drowsiness, dry mouth, bitter mouth, thick sputum, constipation, etc. Rash, increased photosensitivity, hypotension, tachycardia, extrasystoles, anaphylactic shock, hemolytic anemia, leukopenia, thrombocytopenia, Fatigue, Head Pain, Sleep Initiation and Maintenance Disorders, paresthesia, convulsions, hallucinations, reports of hysteria and other adverse reactions. 2. Long-term medication may lead to increased appetite and weight gain. |
| biological activity | Cyproheptadine HCl is the hydrochloride salt form of Cyproheptadine, a histamine receptor antagonist that acts at the 5-HT2 receptor, the IC50 was 0.6 nM. |
| Target | Value |
CAS:
969-33-5
MF:
C21H22ClN
MW:
323.86
EINECS:
213-535-1
MDL No.:
MFCD00012538
Melting point:
254-256.5 °C(Solv: ethanol (64-17-5); ethyl ether (60-29-7))
storage temp.
Inert atmosphere,Room Temperature
solubility
ethanol: soluble
form
solid
color
Crystals from EtOH/Et2O
Water Solubility
Soluble in water (15mM)
Stability:
Hygroscopic
Xi'an Eastling biotech Co., Ltd. is dedicated to the research and development, production, and sales of natural plant extracts; With nearly 15 years of experience in identifying, researching, developing, and producing active ingredients for medicinal plants, we focus on providing innovative products and services to customers in industries such as pharmaceuticals, health food, and cosmetics.
Eastling Biotechnology has established a global direct harvesting system for plant raw materials, ensuring the high quality and authenticity of raw materials, while also protecting the continuity and diversity of plants; Having strong research and development capabilities, we can develop more effective and specialized plant active ingredients for the pharmaceutical, health food, and cosmetics industries; We have established an advanced quality control system, and the quality control of our products depends on advanced testing instruments and high-level technical experts. The effective combination of the two forms Eastling's ability to quickly and rigorously control product quality.
We have a production system that complies with Chinese GMP and American cGMP certifications, as well as advanced and optimized large-scale industrial production technology. In addition to producing specific products for Eastling Biotechnology, we also provide customized services to meet the characteristics and needs of different customers to produce customized products.
We believe that natural active ingredients are the foundation of our service to customers. Scientific and effective production technology is the foundation for us to provide customers with specialized products. We have the ability to serve customers in the pharmaceutical, health food, and cosmetics industries, provide new product solutions, and add new value to their products.