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Xi`an Eastling Biotech Co., Ltd.

Country: China (Mainland)

Business Type:Lab/Research institutions

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Tel: +86-156-91766041

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Tel: +86-156-91766041

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URL: http://www.eastlingbiotech.com/

Province/state: Shaanxi

City: Xi'an city

Street: No. 201, Unit 4, Building 9, Hongqi Community, Tanjia Street, Weiyang District, Xi 'an, Shaanxi

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Factory high quality pepsin 500-10000NFU

CAS NO.9001-75-6

  • FOB Price: USD: 55.00-66.00 /Kilogram Get Latest Price
  • Min.Order: 1 Gram
  • Payment Terms: L/C,T/T,Other
  • Available Specifications:

    98%(500-1000)Kilogram98%(100-500)Metric Ton

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Product Details

Keywords

  • pepsin
  • 9001-75-6
  • pepsin 3000

Quick Details

  • ProName: Factory high quality pepsin 500-10000N...
  • CasNo: 9001-75-6
  • Molecular Formula: n.a.
  • Appearance: white powder
  • Application: Dietary supplements;Food;Additives;Pha...
  • DeliveryTime: 7
  • PackAge: 1kg/bag,5kg/bag,25kg/drum
  • Port: any port in china
  • ProductionCapacity: 1 Metric Ton/Day
  • Purity: purity 98%-101%
  • Storage: 20°
  • Transportation: 20
  • LimitNum: 1 Gram
  • Related Substances: 1
  • Residue on Ignition: 1
  • Heavy Metal: 1
  • Valid Period: 1

Superiority

9001-75-6 - Physico-chemical Properties

Molecular Formula n.a.
Density 1.287 g/cm3
Specific Rotation(α) D26 -64.5° (water pH 4.6)
Water Solubility Soluble in water and dilute aqueous buffers
Solubility Easily soluble in water, milky white to varying degrees, almost insoluble in alcohol, chloroform and ether. The aqueous solution is heated to 70 ℃ or its activity is quickly destroyed in alkaline solution, but its dried product can be heat-resistant to 100 ℃ and hygroscopic
Appearance White-like powder
Color slightly beige
Odor Odorless
Merck 13,7225
Storage Condition -20°C
Stability Stable. Incompatible with strong bases, alkalies, metallic salts, alcohols.
Sensitive Hygroscopic
MDL MFCD00081840
Physical and Chemical Properties This product is pepsin extracted from the gastric mucosa of pigs, sheep or cattle. It is a white or light yellow powder. Soluble in water, the aqueous solution is acidic. Isoelectric point pH = 1. Insoluble in ethanol, chloroform, ether. Non-toxic, with a special smell of meat; It is hygroscopic. Dry enzyme is relatively stable, heating to 1000C for 10min without inactivation. The aqueous solution starts to inactivate when heated to above 700C or above pH 6.2, and is irreversibly inactivated when pH>8. It is stable in strong acidic solution, and the optimum pH is 1.5~2. Its digestibility is strongest when it contains 0.2% ~ 0.4% hydrochloric acid (pH1.6 ~ 1.8), so it is often combined with dilute hydrochloric acid. Sugar-containing gastric protein enzyme preparation: this strain of pepsin is a white or light yellow powder diluted with lactose, glucose or sucrose; it is sweet, without mildew, and has a special smell of meat; it is insoluble in ethanol, ether, and chloroform; it is hygroscopic; the aqueous solution is acidic, and lg can digest 600g of solidified egg protein.
Use Digestive medicine, used for the lack of pepsin or digestive dysfunction caused by indigestion

 

  • This product is pepsin extracted from the gastric mucosa of pigs, sheep or cattle, white or light yellow powder. No mildew, mildew or malodor, with hygroscopicity. Soluble in water, acidic aqueous solution; Difficult to dissolve in ethanol, chloroform, ether. Dry enzyme is more stable, heat to 100 degrees C, 10 min does not live. In the water heated above 70 ℃ or pH value of more than 6.2 start inactivation, pH>8 is irreversible inactivation. It is more stable in acidic solution. The relative molecular mass of crystalline pepsin was 34500, the isoelectric point was pl = 1, and the optimum pH was 1.5~2. Pharmaceutical pepsin is a mixture of various proteolytic enzymes, containing pepsin, cathepsin, collagenase, etc., as a crude enzyme preparation. It can hydrolyze most natural protein substrates, including keratin, mucin, silk protein, protamine, etc., and is especially sensitive to peptide bonds composed of two adjacent aromatic amino acids. The hydrolysis of protein is not complete, and the products are peptone, peptide and amino acid. Its digestion to contain 0.2% ~ 0.4 hydrochloric acid (pH l.6 ~ 1.8) is the strongest, it is often combined with dilute hydrochloric acid.
  • in nature, it is present in the gastric juice of mammals, birds, reptiles and fish, in the form of zymogen in the main cells of the gastric fundus, mainly in the base of the gastric mucosa.
  • 200kg of pig gastric mucosa was added into a sandwich pot containing lOOmL water and 3.8L hydrochloric acid under stirring. When heated to 50 ℃, the acidity was homogenized by accelerating stirring, the temperature was maintained at 45-48 °c for 3-4 hours of digestion, the undigested residue was removed by filtration, and the filtrate was collected. The filtrate was stirred at room temperature to add 15% to 20% of chloroform or diethyl ether, homogenized and then transferred to a precipitating degreaser, allowed to stand for 1 to 2 days to completely precipitate impurities, filtered, and the clear liquid was separated. The clear solution was concentrated to about 1/4 of the original volume under reduced pressure below 40 °c. The concentrated enzyme solution was vacuum-dried and ball-milled to 80-100 mesh to obtain pepsin powder.
  • can also be extracted from the gastric mucosa of sheep and cattle.
What is pepsin pepsin is the main digestive enzyme in gastric juice, which is synthesized by amino acids in the main cells of gastric glands. When food is digested, pepsin is excreted into the gastric cavity to participate in digestion, when the digestive activity is stopped, the synthesis is resumed to supplement the consumption, so that the pepsin can always have sufficient reserve grain.
pepsin is the "main force" in the digestion of food, but the initial discharge from the main cell is not pepsin, but its precursor-pepsinogen. If pepsin is a small knife, Pepsinogen is like a small knife with a "knife sheath" and has no digestive function, but once you encounter an "old partner"-gastric acid and a little pepsin, there is a small knife out of the sheath, immediately into a digestive pepsin, become the "force" to digest food, "killing gas" to digest the various proteins in food, hydrolyzed protein molecules in all peptide bond attachment, the protein becomes a simple structure of the components, these relatively simple components, it is easy to be completely digested in the small intestine.
pepsin and gastric acid are typical "best friends", they are the same product of gastric mucosal glands, although the subtle parts are different; Proteinogen is activated by gastric acid; Gastric acid treated protein, pepsin digestion is the most labor-saving; Gastric acid provides the most suitable working environment for pepsin; The content of pepsin is the "mirror" of the level of gastric acid ", both are" inseparable ", one is lacking, the other is often insufficient, and vice versa.

Details

Pepsin

 

CAS:

9001-75-6

MF:

n.a.

MW:

0

EINECS:

232-629-3

MDL No.:

MFCD00164012

Properties

alpha 

D26 -64.5° (water pH 4.6)

Density 

1.287 g/cm3

storage temp. 

-20°C

solubility 

10 mM HCl: soluble1.0mg/mL, clear to faintly turbid, colorless

form 

powder

color 

slightly beige

Odor

Odorless

Water Solubility 

Soluble in water and dilute aqueous buffers

Sensitive 

Hygroscopic

Merck 

13,7225

Stability:

Stable. Incompatible with strong bases, alkalies, metallic salts, alcohols.

Xi'an Eastling biotech Co., Ltd. is dedicated to the research and development, production, and sales of natural plant extracts; With nearly 15 years of experience in identifying, researching, developing, and producing active ingredients for medicinal plants, we focus on providing innovative products and services to customers in industries such as pharmaceuticals, health food, and cosmetics.

 

Eastling Biotechnology has established a global direct harvesting system for plant raw materials, ensuring the high quality and authenticity of raw materials, while also protecting the continuity and diversity of plants; Having strong research and development capabilities, we can develop more effective and specialized plant active ingredients for the pharmaceutical, health food, and cosmetics industries; We have established an advanced quality control system, and the quality control of our products depends on advanced testing instruments and high-level technical experts. The effective combination of the two forms Eastling's ability to quickly and rigorously control product quality.

 

We have a production system that complies with Chinese GMP and American cGMP certifications, as well as advanced and optimized large-scale industrial production technology. In addition to producing specific products for Eastling Biotechnology, we also provide customized services to meet the characteristics and needs of different customers to produce customized products.

We believe that natural active ingredients are the foundation of our service to customers. Scientific and effective production technology is the foundation for us to provide customers with specialized products. We have the ability to serve customers in the pharmaceutical, health food, and cosmetics industries, provide new product solutions, and add new value to their products.