Keywords

• Azithromycin
• 83905-01-5
• Azithromycin

Quick Details

• ProName: Factory high quality Azithromycin
• CasNo: 83905-01-5
• Molecular Formula: C38H72N2O12
• Appearance: white powder
• Application: Dietary supplements;Food;Additives;Pha...
• DeliveryTime: 7
• PackAge: 1kg/bag,5kg/bag,25kg/drum
• Port: any port in china
• ProductionCapacity: 1 Kilogram/Day
• Purity: purity 98%-101%
• Storage: 20℃
• Transportation: low temp
• LimitNum: 1 Gram
• Related Substances: 1
• Residue on Ignition: 1
• Heavy Metal: 1
• Valid Period: 1

Superiority

83905-01-5 - Physico-chemical Properties

1. take this product, add anhydrous ethanol to dissolve and dilute to make a solution containing about 5mg per 1 ml as a test solution; Take an appropriate amount of azithromycin reference substance, add absolute ethanol to dissolve and dilute to prepare a solution containing about 5mg per 1 ml as a reference solution; According to thin layer chromatography (General 0502) test, absorb the above solutions respectively on the same silica gel G thin layer plate, with ethyl acetate-n-hexane-diethylamine (10:10:2) as the developing solvent, spread out, dry, spray with color developer (take sodium molybdate 2.5g, cerium sulfate lg, add 10% sulfuric acid solution to dissolve and dilute to 105 ml), heating at ° C. For several minutes. The position and color of the main spot displayed by the test solution should be the same as the position and color of the main spot of the reference solution.
2. in the chromatogram recorded under the content determination item, the retention time of the main peak of the test solution should be consistent with the retention time of the main peak of the reference solution.
3. The infrared absorption spectrum of this product should be consistent with that of the control (Spectrum set 772) or with that of the control. (In case of inconsistency, the appropriate amount of this product and the reference product should be taken, dissolved in acetone respectively, and volatilized to dryness at room temperature for determination.)
4. two items (1) and (2) above can be selected as one item.
5. developed by Pfizer Inc., USA, launched in 1988. Macrolide antibiotics, the antibacterial mechanism is similar to erythromycin, but the antibacterial spectrum is wider; The antibacterial activity of gram-positive bacteria is stronger, and the Gram-negative bacteria such as Haemophilus influenzae, salmonella, Escherichia coli, the antibacterial activity of Shigella was also strong. It has a good therapeutic effect on respiratory tract infection, skin and soft tissue infection and diseases caused by sensitive strains.

Details

Azithromycin

CAS:

83905-01-5

MF:

C38H72N2O12

MW:

748.98

EINECS:

617-500-5

MDL No.:

MFCD00873574

Properties

Melting point:

113-115°C

alpha 

D20 -37° (c = 1 in CHCl3)

Boiling point:

822.1±65.0 °C(Predicted)

Density 

1.18±0.1 g/cm3(Predicted)

storage temp. 

Sealed in dry,2-8°C

solubility 

Practically insoluble in water, freely soluble in anhydrous ethanol and in methylene chloride.

pka

pKa 8.74 (H2O t=25 I=0.167) (Uncertain);9.45(H2O t=25 I=0.167) (Uncertain)

color 

White to Off-White

optical activity

[α]/D 45±2°, c = 1% in ethanol

BCS Class

4

Stability:

Stable. Incompatible with strong oxidizing agents.

Xi'an Eastling biotech Co., Ltd. is dedicated to the research and development, production, and sales of natural plant extracts; With nearly 15 years of experience in identifying, researching, developing, and producing active ingredients for medicinal plants, we focus on providing innovative products and services to customers in industries such as pharmaceuticals, health food, and cosmetics.

Eastling Biotechnology has established a global direct harvesting system for plant raw materials, ensuring the high quality and authenticity of raw materials, while also protecting the continuity and diversity of plants; Having strong research and development capabilities, we can develop more effective and specialized plant active ingredients for the pharmaceutical, health food, and cosmetics industries; We have established an advanced quality control system, and the quality control of our products depends on advanced testing instruments and high-level technical experts. The effective combination of the two forms Eastling's ability to quickly and rigorously control product quality.

We have a production system that complies with Chinese GMP and American cGMP certifications, as well as advanced and optimized large-scale industrial production technology. In addition to producing specific products for Eastling Biotechnology, we also provide customized services to meet the characteristics and needs of different customers to produce customized products.

We believe that natural active ingredients are the foundation of our service to customers. Scientific and effective production technology is the foundation for us to provide customers with specialized products. We have the ability to serve customers in the pharmaceutical, health food, and cosmetics industries, provide new product solutions, and add new value to their products.