Xi`an Eastling Biotech Co., Ltd.
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Business Type:Lab/Research institutions
Tel: +86-156-91766041
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Tel: +86-156-91766041
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URL: http://www.eastlingbiotech.com/
Province/state: Shaanxi
City: Xi'an city
Street: No. 201, Unit 4, Building 9, Hongqi Community, Tanjia Street, Weiyang District, Xi 'an, Shaanxi
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CAS NO.6805-41-0
98%(1-25)Kilogram98%(26-500)Kilogram98%(501-1000)Kilogram
Aescine
CAS: 6805-41-0
Molecular Formula: C55H86O24
| Molecular Formula | C55H86O24 |
| Molar Mass | 1131.26 |
| Density | 1.1200 (rough estimate) |
| Melting Point | 224.5°C |
| Boling Point | 764.81°C (rough estimate) |
| Flash Point | 311.8°C |
| Solubility | Soluble in methanol. |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | White powder |
| Color | white |
| Merck | 13,3730 |
| Storage Condition | 2-8℃ |
| Sensitive | Easily absorbing moisture |
| Refractive Index | 1.6500 (estimate) |
| MDL | MFCD00076054 |
| In vitro study | Escin can effectively inhibit the proliferation of pancreatic cancer cells, but it has little effect on normal skeletal muscle cells. Escin enhances the proliferation-inhibiting and apoptosis-inducing effects of gemcitabine in BxPC-3 and PANC-1 cells. Escin also downregulates the activation of gemcitabine-induced NF-kB and its downstream gene products in pancreatic cancer cells. |
| In vivo study | Escin enhances the therapeutic effect of gemcitabine in nude mice bearing BxPC-3 xenografts. Ecin and gemcitabine have a significant synergistic effect on inhibiting the growth of pancreatic tumors, inhibiting proliferation and inducing apoptosis of tumor cells. Escin enhances the inhibitory effect of gemcitabine on NF-kB and NF-kB regulated gene products. |
| efficacy | The extracts from horse chestnut and horse chestnut, which promote the synthesis of pectin and repair damaged skin, can effectively moisturizing rich flavonoids, with natural strong anti-aging anti-wrinkle effect, can improve some eye skin blood circulation, and can also eliminate cellulite, dark circles and eye bags have some effect. |
| trait | brownish yellow to white crystalline powder; Slightly gas, bitter. |
| Use | Escin has the advantages of anti-tissue edema, reducing vascular permeability and preventing water accumulation in tissues, rapid elimination of the feeling of heaviness and pressure caused by local edema. It can be used to treat stomach cold pain, abdominal distention, Veratrum pain, malaria, dysentery. |
| biological activity | Escin (Aescin) is a mixture of saponins found in Aesculus chinensis Bunge, vascular protection. |
Mol Download Chemical properties
CAS:
6805-41-0
MF:
C55H86O24
MW:
1131.26
EINECS:
229-880-6
MDL No.:
MFCD00046289
Melting point:
224.5°C
Boiling point:
764.81°C (rough estimate)
Density
1.1200 (rough estimate)
refractive index
1.6500 (estimate)
storage temp.
4°C, protect from light
solubility
Soluble in methanol.
form
powder
color
white
Merck
13,3730
Stability:
Hygroscopic
Xi'an Eastling biotech Co., Ltd. is dedicated to the research and development, production, and sales of natural plant extracts; With nearly 15 years of experience in identifying, researching, developing, and producing active ingredients for medicinal plants, we focus on providing innovative products and services to customers in industries such as pharmaceuticals, health food, and cosmetics.
Eastling Biotechnology has established a global direct harvesting system for plant raw materials, ensuring the high quality and authenticity of raw materials, while also protecting the continuity and diversity of plants; Having strong research and development capabilities, we can develop more effective and specialized plant active ingredients for the pharmaceutical, health food, and cosmetics industries; We have established an advanced quality control system, and the quality control of our products depends on advanced testing instruments and high-level technical experts. The effective combination of the two forms Eastling's ability to quickly and rigorously control product quality.
We have a production system that complies with Chinese GMP and American cGMP certifications, as well as advanced and optimized large-scale industrial production technology. In addition to producing specific products for Eastling Biotechnology, we also provide customized services to meet the characteristics and needs of different customers to produce customized products.
We believe that natural active ingredients are the foundation of our service to customers. Scientific and effective production technology is the foundation for us to provide customers with specialized products. We have the ability to serve customers in the pharmaceutical, health food, and cosmetics industries, provide new product solutions, and add new value to their products.