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CAS NO.568-72-9
98%(1-25)Kilogram98%(26-500)Kilogram98%(501-1000)Kilogram
Tanshinone IIA
CAS: 568-72-9
Molecular Formula: C19H18O3
Name | Tanshinone IIA |
Synonyms | NSC 686518 tanshiones Tanshinone B Tanshinon II Tanshinone II TANSHINONE IIA Tanshinone IIA AKOS NCG1-0066 Dan Shen Ketone Tanshinone II A TANSHINONES IIA 1,6-dimethylphenanthro[1,2-b]furan-10,11-dione 3,8,8-TRIMETHYL-8,9,10,11-TETRAHYDROPHENANTHRO[1,2-B]FURAN-1,2-DIONE 1,6,6-trimethyl-6,7,8,9-tetrahydrophenanthro[1,2-b]furan-10,11-dione 1,6,6-TRIMETHYL-6,7,8,9-TETRAHYDRO-PHENANTHRO[1,2-B]FURAN-10,11-DIONE 1,6,6-trimethyl-1,2,6,7,8,9-hexahydrophenanthro[1,2-b]furan-10,11-dione Phenanthro(1,2-b)furan-10,11-dione, 6,7,8,9-tetrahydro-1,6,6-trimethyl- |
CAS | 568-72-9 |
InChI | InChI=1/C19H20O3/c1-10-9-22-18-12-6-7-13-11(5-4-8-19(13,2)3)15(12)17(21)16(20)14(10)18/h6-7,10H,4-5,8-9H2,1-3H3 |
InChIKey | HYXITZLLTYIPOF-UHFFFAOYSA-N |
Molecular Formula | C19H18O3 |
Molar Mass | 294.34 |
Density | 1.209±0.06 g/cm3(Predicted) |
Melting Point | 196.0 to 200.0 °C |
Boling Point | 480.7±44.0 °C(Predicted) |
Flash Point | 203.381°C |
Solubility | Soluble in ethanol, acetone, ether, benzene and other organic solvents, slightly soluble in water. |
Vapor Presure | 0mmHg at 25°C |
Appearance | Orange red needle crystal |
Color | Orange |
Storage Condition | 2-8°C |
Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months. |
Refractive Index | 1.603 |
MDL | MFCD00238692 |
Physical and Chemical Properties | Red Crystal, soluble in ethanol, acetone, ether benzene, slightly soluble in water, derived from Salvia miltiorrhiza. |
Plant Source: | Salvia miltiorrhiza |
Use | Tanshinone IIA is a derivative of Tanshinone, which can inhibit tumor growth in vivo. It also maintains vasodilatory activity in vivo. Tanshinone IIA has the following effects: ① improving coronary circulation; ② repairing effect of vascular endothelial cells; ③ anti-atherosclerosis (AS) formation; ④ anti-myocardial hypertrophy; the prevention and treatment of diabetic complications can be used for clinical coronary heart disease, angina, myocardial infarction, can also be used for ventricular premature beat. for content determination/identification/pharmacological experiments. Pharmacological Efficacy: mainly used for the treatment of cardiovascular disease, with the expansion of blood vessels, blood pressure, anti-thrombotic function, the treatment of coronary heart disease, angina pectoris, tachycardia has a significant effect. |
trait | Tanshinone IIA is orange-red needle-like crystal (EtOAc), mp 209-210 ℃. Soluble in ethanol, acetone, ether, benzene and other organic solvents, slightly soluble in water. |
pharmacological effects | Tanshinone IIA is mainly used for the treatment of cardiovascular disease, with the function of expanding blood vessels, lowering blood pressure, for the treatment of coronary heart disease, angina pectoris, tachycardia has a significant effect. |
preparation method | Tanshinone IIA is mainly completed by extraction, chromatography, crystallization and other processes. |
CAS:
568-72-9
MF:
C19H18O3
MW:
294.34
EINECS:
MDL No.:
MFCD00238692
Melting point:
196.0 to 200.0 °C
Boiling point:
480.7±44.0 °C(Predicted)
Density
1.209±0.06 g/cm3(Predicted)
storage temp.
2-8°C
solubility
methanol: soluble5mg/mL, clear, red-orange to red
form
powder, red
color
Orange
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKey
HYXITZLLTYIPOF-UHFFFAOYSA-N
LogP
4.925 (est)
Xi'an Eastling biotech Co., Ltd. is dedicated to the research and development, production, and sales of natural plant extracts; With nearly 15 years of experience in identifying, researching, developing, and producing active ingredients for medicinal plants, we focus on providing innovative products and services to customers in industries such as pharmaceuticals, health food, and cosmetics.
Eastling Biotechnology has established a global direct harvesting system for plant raw materials, ensuring the high quality and authenticity of raw materials, while also protecting the continuity and diversity of plants; Having strong research and development capabilities, we can develop more effective and specialized plant active ingredients for the pharmaceutical, health food, and cosmetics industries; We have established an advanced quality control system, and the quality control of our products depends on advanced testing instruments and high-level technical experts. The effective combination of the two forms Eastling's ability to quickly and rigorously control product quality.
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