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CAS NO.528-48-3
98%(1-25)Kilogram98%(26-500)Kilogram98%(501-1000)Kilogram
| Molecular Formula | C15H10O6 |
| Molar Mass | 286.24 |
| Density | 1.2981 (rough estimate) |
| Melting Point | >330°C(lit.) |
| Boling Point | 348.61°C (rough estimate) |
| Flash Point | 233°C |
| Solubility | Soluble in ethanol, acetone and acetic acid. Almost insoluble in water, ether, benzene, chloroform and petroleum ether. |
| Vapor Presure | 3.23E-15mmHg at 25°C |
| Appearance | Yellow needle crystal (dilute ethanol) |
| Color | Pale Yellow to Very Dark Yellow |
| Merck | 14,4088 |
| BRN | 292829 |
| pKa | 6.83±0.40(Predicted) |
| Storage Condition | Sealed in dry,Store in freezer, under -20°C |
| Stability | Hygroscopic |
| Refractive Index | 1.4413 (estimate) |
| MDL | MFCD00006829 |
| Physical and Chemical Properties | Soluble in ethanol, acetone and acetic acid. Almost insoluble in water, ether, benzene, chloroform and petroleum ether. It is derived from the plants such as wood and tree Rhus suce Danea L Wood |
| overview | luffin (Fisetin) is a polymer pharmaceutical raw material. This product is a yellow needle-like crystal, derived from the lacquer family plants, wax tree RhussuccedaneaL, coggygria, etc. Soluble in ethanol, acetone and acetic acid. Almost insoluble in water, ether, benzene, chloroform and petroleum ether. It has an inhibitory effect on the production of prostate cord in 3T3 mice fibroblasts with methylcholanthracene transmutation, and the half effective inhibitory concentration (ID50) is 42.0UM. It has inhibitory effect on the whole sugar reductase of rat eye lens, and the half effective inhibitory concentration is 10-6M; for mouse small intestine specimens, its anti-acetylcholine spasmodic effect is the 166% of papaverine. A team of Japanese and American researchers found through animal experiments that the lutein in vegetables and fruits can help improve memory. |
| detection method | HPLC ≥ 98% |
| specifications | 10 mg20mg100mg500mg1g (can be packaged according to customer requirements) |
| traits | this product is yellow needle crystal |
| function and use | this product is used for content determination. |
| extraction source | this product is extract of sumac plant fig. 1 one of the sources of envery flavin-coggygria extract |
| physical properties | yellow needle crystal (dilute ethanol), melting point 330 ℃ (decomposition). Soluble in ethanol, acetone and acetic acid. Almost insoluble in water, ether, benzene, chloroform and petroleum ether. Melting point 348 ℃, bright yellow fine needle crystal , melting point> 300 ℃ |
| pharmacological action | 1. inhibition of prostaglandin: inhibitory effect on the formation of prostatic cord in 3T3 mouse fibroblasts transformed from methylcholanthracene, with a half effective inhibitory concentration (ID50) of 42.0UM. 2. Enzyme inhibition: it has inhibitory effect on the whole sugar reductase of rat eye lens, and the half effective inhibitory concentration is 10-6M 3. antispasmodic: on mouse small intestine specimens, its antiacetylcholine spasmodic effect is the 166% of papaverine. 4. A team composed of Japanese and American researchers found through animal experiments that the lutein in vegetables and fruits can help improve memory. |
| extraction rate experiment | 20g of yellow protection was weighed, totaling 5 batches. Under the optimal extraction process, reflux extraction until the extract is nearly colorless, combine the extract, filter and concentrate, move to a 1000ml volumetric flask, add ethanol to the scale, and shake well. accurately absorb 1ml and place it in a 100ml volumetric flask, add ethanol to dilute to scale, shake well, measure its absorbance at 367±1nm wavelength of ultraviolet spectrophotometer according to the determination method of envery flavin content in yellow pond pulp, calculate the content and extraction rate of envery flavin in the sample according to the 847.52 of C12H10O6 absorption coefficient, and see table 1 for the results. table 1 extraction rate of luffin in coggygria coggygria |
| references | [1] lutein. Bailian database.[2017/08.20] [2] Fisetin.[2017/08.20] [3] Tang Jianhua, Shen Qingliang. Study on extraction rate of luffin from Cotinus coggygria [J]. Chinese patent medicine, 1992,(08):10. |
| use | used for content determination/identification/pharmacological experiments, etc. Pharmacological effects: 1. Inhibition of prostaglandins: It has an inhibitory effect on the formation of the prostate cord of 3T3 mice fibroblasts mutated by methylcholanthracene, and the half effective inhibitory concentration (ID50) is 42.0UM. 2. Enzyme inhibition: It has inhibitory effect on the whole sugar reductase of rat eye lens, and the half effective inhibitory concentration is 10-6M. 3. Antispasmodic: For small intestine specimens of mice, its antispasmodic effect against acetylcholine is the 166% of papaverine. 4. A team of Japanese and American researchers found through animal experiments that the lutein in vegetables and fruits can help improve memory. a naturally occurring flavonol with therapeutic activity, used to synthesize anti-inflammatory, anticonvulsant and antiproliferative drugs with pharmaceutical activity. |
CAS:
528-48-3
MF:
C15H10O6
MW:
286.24
EINECS:
208-434-4
MDL No.:
MFCD00006829
Melting point:
>330 °C(lit.)
Boiling point:
348.61°C (rough estimate)
Density
1.2981 (rough estimate)
refractive index
1.4413 (estimate)
storage temp.
Sealed in dry,Store in freezer, under -20°C
solubility
DMSO (Slightly), Methanol (Slightly)
pka
6.83±0.40(Predicted)
form
Solid
Colour Index
75620
color
Pale Yellow to Very Dark Yellow
Merck
14,4088
BRN
292829
Stability:
Hygroscopic
InChI
InChI=1S/C15H10O6/c16-8-2-3-9-12(6-8)21-15(14(20)13(9)19)7-1-4-10(17)11(18)5-7/h1-6,16-18,20H
InChIKey
XHEFDIBZLJXQHF-UHFFFAOYSA-N
SMILES
C1(C2=CC=C(O)C(O)=C2)OC2=CC(O)=CC=C2C(=O)C=1O
LogP
1.970 (est)
Xi'an Eastling biotech Co., Ltd. is dedicated to the research and development, production, and sales of natural plant extracts; With nearly 15 years of experience in identifying, researching, developing, and producing active ingredients for medicinal plants, we focus on providing innovative products and services to customers in industries such as pharmaceuticals, health food, and cosmetics.
Eastling Biotechnology has established a global direct harvesting system for plant raw materials, ensuring the high quality and authenticity of raw materials, while also protecting the continuity and diversity of plants; Having strong research and development capabilities, we can develop more effective and specialized plant active ingredients for the pharmaceutical, health food, and cosmetics industries; We have established an advanced quality control system, and the quality control of our products depends on advanced testing instruments and high-level technical experts. The effective combination of the two forms Eastling's ability to quickly and rigorously control product quality.
We have a production system that complies with Chinese GMP and American cGMP certifications, as well as advanced and optimized large-scale industrial production technology. In addition to producing specific products for Eastling Biotechnology, we also provide customized services to meet the characteristics and needs of different customers to produce customized products.
We believe that natural active ingredients are the foundation of our service to customers. Scientific and effective production technology is the foundation for us to provide customers with specialized products. We have the ability to serve customers in the pharmaceutical, health food, and cosmetics industries, provide new product solutions, and add new value to their products.