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CAS NO.497-30-3
99%(1-500)Kilogram99%(501-1000)Kilogram
Ergothioneine
CAS: 497-30-3
Molecular Formula: C9H15N3O2S
| Molecular Formula | C9H15N3O2S |
| Molar Mass | 229.3 |
| Density | 1.2541 (rough estimate) |
| Melting Point | 275-277°C (dec.) |
| Solubility | Soluble in water (50 mg/ml), acetone, hot ethanol, and methanol. |
| Appearance | White solid. |
| Color | White or off-white |
| PH | +47^o (c=1 in water) |
| Storage Condition | -20°C |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in water may be stored at -20°C for no more then 1 day. |
| Refractive Index | 1.6740 (estimate) |
| MDL | MFCD00167474 |
| Introduction | ergothionine is a natural antioxidant, which can protect cells in the human body, is an important active substance in the body. Natural antioxidants are safe and non-toxic, and have become a research hotspot. As a natural antioxidant, ergothionine has come into people's field of vision. It has many physiological functions, such as scavenging free radicals, detoxification, maintaining DNA biosynthesis, normal growth of cells and cellular immunity. Ergothionein is a natural molecule isolated from the rye ergot fungus and later found in rat red blood cells, liver and many other animal tissues. Its antioxidant properties may provide potential for complex therapy, or as a food additive or cosmetic. |
| Use | L-ergothionein is a natural molecule isolated from the rye ergot fungus, later found in rat erythrocytes and liver, as well as in many other animal tissues. Its antioxidant properties may provide the therapeutic potential of the compound, or it may be used as a food additive or cosmetic. |
| distribution range | ergothionein is distributed in some tissues and organs of mammals, mainly in red blood cells (about 1~2 mmol.L) and in the semen of some animals, although no experimental studies have shown that animals can synthesize the substance, but there must be a way to absorb and retain ergothio in animal cells. For predators, ergothionein in animal tissues can supply dietary needs. A study by Melville.D.B and Eich. S[1] found that ergothionein was also present in cereals. |
| biological effects | ergothioneine is a powerful hypochlorous acid scavenger (HOCl), although many compounds can react with hypochlorous acid, few can react as rapidly as ergosulfide. a 1-anti-protease inhibitors (APIs), such as elastase, are particularly sensitive to hypochlorous acid, and physiological concentrations of ergothio are very effective in protecting APIs, against the inactivation induced by hypochlorous acid, since neutrophils are the main source of hypochlorous acid in the body, one of the roles of ergothionein is to protect red blood cells from the harm of neutrophils from normal functioning or pathological sites of inflammation. |
| Application | ergothionine in organ transplantation, cell preservation, medicine, food and beverage, functional food, animal feed, cosmetics and biotechnology and other fields have a wide range of uses and market prospects. used as a unique antioxidant: ergothionine is a highly protective and non-toxic natural antioxidant for cells, which is not easily oxidized in water, this allows their concentration in certain tissues to reach mmol, and stimulates the natural antioxidant defense system of cells. Among many antioxidants, ergothionein is especially unique, because ergothionein can chelate heavy metal ions, which can protect red blood cells from free radical damage. |
| biological activity | Ergothioneine is an imidazole-2-thione derivative of histidine betaine, it is synthesized by certain bacteria and fungi. Ergothioneine is generally considered an antioxidant. |
Mol Download Chemical properties
CAS:
497-30-3
MF:
C9H15N3O2S
MW:
229.3
EINECS:
207-843-5
MDL No.:
MFCD00167474
Melting point:
275-277°C (dec.)
Density
1.2541 (rough estimate)
refractive index
1.6740 (estimate)
storage temp.
-20°C
solubility
Soluble in Water (up to 10 mg/ml)
form
White solid.
color
White or off-white
PH
+47^o (c=1 in water)
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in water may be stored at -20°C for no more then 1 day.
InChI
InChI=1/C9H15N3O2S/c1-12(2,3)7(8(13)14)4-6-5-10-9(15)11-6/h5,7H,4H2,1-3H3,(H2-,10,11,13,14,15)/t7-/s3
InChIKey
SSISHJJTAXXQAX-KPOCXSGKNA-N
SMILES
[N+](C)(C)(C)[C@@H](CC1=CNC(S)=N1)C([O-])=O |&1:4,r|
Xi'an Eastling biotech Co., Ltd. is dedicated to the research and development, production, and sales of natural plant extracts; With nearly 15 years of experience in identifying, researching, developing, and producing active ingredients for medicinal plants, we focus on providing innovative products and services to customers in industries such as pharmaceuticals, health food, and cosmetics.
Eastling Biotechnology has established a global direct harvesting system for plant raw materials, ensuring the high quality and authenticity of raw materials, while also protecting the continuity and diversity of plants; Having strong research and development capabilities, we can develop more effective and specialized plant active ingredients for the pharmaceutical, health food, and cosmetics industries; We have established an advanced quality control system, and the quality control of our products depends on advanced testing instruments and high-level technical experts. The effective combination of the two forms Eastling's ability to quickly and rigorously control product quality.
We have a production system that complies with Chinese GMP and American cGMP certifications, as well as advanced and optimized large-scale industrial production technology. In addition to producing specific products for Eastling Biotechnology, we also provide customized services to meet the characteristics and needs of different customers to produce customized products.
We believe that natural active ingredients are the foundation of our service to customers. Scientific and effective production technology is the foundation for us to provide customers with specialized products. We have the ability to serve customers in the pharmaceutical, health food, and cosmetics industries, provide new product solutions, and add new value to their products.