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CAS NO.491-54-3
98%(1-25)Kilogram98%(26-500)Kilogram98%(501-1000)Kilogram
CAS: 491-54-3
Molecular Formula: C16H12O6
| Name | 4'-Methoxy-3,5,7-trihydroxyflavone |
| Synonyms | Kaemperide KAEMPFERIDE Kaempferide ARTEMISIA ANNUA 4'-methylkaempferol 3,5,7-Trihydroxy-4-methoxyflavone 4'-Methoxy-3,5,7-trihydroxyflavone Kaempferide~3,5,7-Trihydroxy-4-methoxyflavone 3,5,7-Trihydroxy-2-(4-methoxy-phenyl)-chromen-4- 3,5,7-trihydroxy-2-(4-methoxyphenyl)-4-benzopyrone 3,5,7-trihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one 3,5,7-trihydroxy-2-(4-methoxyphenyl)-1-benzopyran-4-one |
| CAS | 491-54-3 |
| EINECS | 207-738-4 |
| InChI | InChI=1/C16H12O6/c1-21-10-4-2-8(3-5-10)16-15(20)14(19)13-11(18)6-9(17)7-12(13)22-16/h2-7,17-18,20H,1H3 |
| Molecular Formula | C16H12O6 |
| Molar Mass | 300.26 |
| Density | 1.538 |
| Melting Point | 156-157°C(lit.) |
| Boling Point | 543.8±50.0 °C(Predicted) |
| Flash Point | 207.1°C |
| Solubility | Soluble in hot methanol, DMSO and other solvents, insoluble in petroleum ether, ether, chloroform. |
| Vapor Presure | 1.94E-12mmHg at 25°C |
| Appearance | Yellow powder |
| Color | Yellow |
| BRN | 305378 |
| pKa | 6.32±0.40(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
| Refractive Index | 1.709 |
| MDL | MFCD00016771 |
| Physical and Chemical Properties | Yellow needle Crystal, soluble in methanol, ethanol, DMSO and other organic solvents, derived from galangal, Equisetum, VAS, safflower, sedum sarmentosum, Lysimachia. |
| biological activity | Kaempferide (4 '-Methylkaempferol, 4'-O-Methylkaempferol, Kaempferol 4 '-methyl ether) is a natural product extracted from Kaempfera root and has a variety of biological activities, including anti-cancer, anti-inflammatory, antioxidant, antibacterial and antiviral activities. |
| uses | kaempferol has anti-cancer, anti-fertility, anti-epilepsy, anti-inflammatory, antioxidant and anti-ulcer effects. used for content determination/identification/pharmacological experiment, etc. Pharmacological effect: warm pain relief. Treat abdominal cold pain, stop eating, fall and damage. |
generally, sophorae fructus is used as a raw material for extraction. Sophorae fructus was extracted with ethanol, the extract was hydrolyzed with acid to precipitate precipitates, the precipitate was extracted with ether, and the ether extract was examined by polyamide thin layer plate (chloroform: methanol 3:1 as developing solvent), there are mainly 2 spots, imitation of polyamide thin layer chromatography conditions, polyamide column chromatography. Take the polyamide powder (60-120 mesh) llOg and load it into a polyethylene film column with a circumference of 10cm. Stir the sample into the polyamide powder lOg, draw it dry under reduced pressure, finely grind it, load it into the top of the column, and then use chloroform: methanol (3:1) was spread to the bottom of the column. The whole column has two main yellow layer bands, one in the section 17 ~ 21cm from the bottom of the column (with work), the other in the section 17 ~ 34cm from the bottom of the column (with II). The two laminas were cut and eluted with ethanol respectively. The eluate was crystallized with methanol-water to obtain yellow needle crystals, which were genistein. The eluate with Ⅱ was crystallized with chloroform-acetone for 2 times, yellow Fine-leaf crystals were obtained, which were kaempferol.
Mol Download Chemical properties
CAS:
491-54-3
MF:
C16H12O6
MW:
300.26
EINECS:
207-738-4
MDL No.:
MFCD00016771
Melting point:
156-157 °C(lit.)
Boiling point:
543.8±50.0 °C(Predicted)
Density
1.538
storage temp.
Keep in dark place,Inert atmosphere,2-8°C
solubility
Chloroform (Slightly, Heated), DMSO (Slightly, Heated), Methanol (Slightly, Heat
pka
6.32±0.40(Predicted)
color
Yellow
BRN
305378
LogP
2.740 (est)
Xi'an Eastling biotech Co., Ltd. is dedicated to the research and development, production, and sales of natural plant extracts; With nearly 15 years of experience in identifying, researching, developing, and producing active ingredients for medicinal plants, we focus on providing innovative products and services to customers in industries such as pharmaceuticals, health food, and cosmetics.
Eastling Biotechnology has established a global direct harvesting system for plant raw materials, ensuring the high quality and authenticity of raw materials, while also protecting the continuity and diversity of plants; Having strong research and development capabilities, we can develop more effective and specialized plant active ingredients for the pharmaceutical, health food, and cosmetics industries; We have established an advanced quality control system, and the quality control of our products depends on advanced testing instruments and high-level technical experts. The effective combination of the two forms Eastling's ability to quickly and rigorously control product quality.
We have a production system that complies with Chinese GMP and American cGMP certifications, as well as advanced and optimized large-scale industrial production technology. In addition to producing specific products for Eastling Biotechnology, we also provide customized services to meet the characteristics and needs of different customers to produce customized products.
We believe that natural active ingredients are the foundation of our service to customers. Scientific and effective production technology is the foundation for us to provide customers with specialized products. We have the ability to serve customers in the pharmaceutical, health food, and cosmetics industries, provide new product solutions, and add new value to their products.