Product Certification&
Enterprise Certification
Country: China (Mainland)
Business Type:Lab/Research institutions
Tel: +86-156-91766041
Mobile:
Tel: +86-156-91766041
Fax:
URL: http://www.eastlingbiotech.com/
Province/state: Shaanxi
City: Xi'an city
Street: No. 201, Unit 4, Building 9, Hongqi Community, Tanjia Street, Weiyang District, Xi 'an, Shaanxi
MaxCard:
CAS NO.481-29-8
98%(500-1000)Kilogram98%(100-500)Metric Ton
Epiandrosterone
CAS: 481-29-8
Molecular Formula: C19H30O2
Name | Epiandrosterone |
Synonyms | Epiandrosterone Isoandrosterone 3-Epiandrosterone TRANS-ANDROSTERONE 3beta-Androsterone trans-Androsterone 5-Epiandrosterone-17-one 3-hydroxyandrostan-17-one 3-Hydroxyandrostan-17-one 5alpha-Androstan-3beta-ol-17-one (3beta)-3-hydroxyandrostan-17-one 3beta-Hydroxy-5alpha-androstan-17-one 5alpha-Androstan-17-one, 3beta-hydroxy- (3beta,5alpha)-3-hydroxyandrostan-17-one Androstan-17-one, 3-hydroxy-, (3beta,5alpha)- (3beta,5alpha,9beta)-3-hydroxyandrostan-17-one (3beta,5alpha,14beta)-3-hydroxyandrostan-17-one (3beta,5alpha,9beta,14beta)-3-hydroxyandrostan-17-one (3S,5S,8R,10S,13S)-3-Hydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-one |
CAS | 481-29-8 |
EINECS | 207-563-3 |
InChI | InChI=1/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12-16,20H,3-11H2,1-2H3/t12-,13-,14-,15-,16+,18-,19-/m0/s1 |
InChIKey | QGXBDMJGAMFCBF-LUJOEAJASA-N |
Molecular Formula | C19H30O2 |
Molar Mass | 290.45 |
Density | 1.0320 (rough estimate) |
Melting Point | 172-174°C |
Boling Point | 372.52°C (rough estimate) |
Specific Rotation(α) | 91 º (c=1, CH3OH) |
Flash Point | 176.377°C |
Water Solubility | practically insoluble |
Vapor Presure | 0mmHg at 25°C |
Merck | 3609 |
BRN | 1884007 |
pKa | 15.14±0.60(Predicted) |
Storage Condition | Refrigerator |
Refractive Index | 1.4709 (estimate) |
Physical and Chemical Properties | Melting point 171-177°C specific rotation 91 ° (c = 1, CH3OH) water-soluble practically insoluble |
Use | For steroid drugs |
In vitro study | Epiandrosterone is a natural metabolite of Dehydroepiandrosterone(DHEA) by 5α-reductase. Epiandrosterone is formed in peripheral tissues, released into the blood circulation, and finally excreted in the urine. Epiandrosterone acts weakly as an androgen, but is widely believed to inhibit the pentose phosphate pathway (PPP) and reduce intracellular NADPH levels. Epiandrosterone reduces NO-induced pulmonary artery relaxation, although Epiandrosterone acts on isolated lungs, inhibits angiotensin II and hypoxia-induced vasoconstriction, and relaxes isolated pulmonary arteries precontracted with KCl. |
Mol Download Chemical properties
CAS:
481-29-8
MF:
C19H30O2
MW:
290.45
EINECS:
207-563-3
MDL No.:
MFCD00064134
Melting point:
172-174 °C
alpha
91 º (c=1, CH3OH)
Boiling point:
372.52°C (rough estimate)
Density
1.0320 (rough estimate)
refractive index
1.4709 (estimate)
storage temp.
Refrigerator
solubility
insoluble in H2O; ≥12.35 mg/mL in EtOH; ≥28.27 mg/mL in DMSO
pka
15.14±0.60(Predicted)
form
solid
Water Solubility
practically insoluble
Merck
3609
BRN
1884007
InChIKey
QGXBDMJGAMFCBF-LUJOEAJASA-N
LogP
3.751
Xi'an Eastling biotech Co., Ltd. is dedicated to the research and development, production, and sales of natural plant extracts; With nearly 15 years of experience in identifying, researching, developing, and producing active ingredients for medicinal plants, we focus on providing innovative products and services to customers in industries such as pharmaceuticals, health food, and cosmetics.
Eastling Biotechnology has established a global direct harvesting system for plant raw materials, ensuring the high quality and authenticity of raw materials, while also protecting the continuity and diversity of plants; Having strong research and development capabilities, we can develop more effective and specialized plant active ingredients for the pharmaceutical, health food, and cosmetics industries; We have established an advanced quality control system, and the quality control of our products depends on advanced testing instruments and high-level technical experts. The effective combination of the two forms Eastling's ability to quickly and rigorously control product quality.
We have a production system that complies with Chinese GMP and American cGMP certifications, as well as advanced and optimized large-scale industrial production technology. In addition to producing specific products for Eastling Biotechnology, we also provide customized services to meet the characteristics and needs of different customers to produce customized products.
We believe that natural active ingredients are the foundation of our service to customers. Scientific and effective production technology is the foundation for us to provide customers with specialized products. We have the ability to serve customers in the pharmaceutical, health food, and cosmetics industries, provide new product solutions, and add new value to their products.