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CAS NO.21967-41-9
98%(500-1000)Kilogram98%(100-500)Metric Ton
| Molecular Formula | C21H18O11 | ||||||
| Molar Mass | 446.36 | ||||||
| Density | 1.737±0.06 g/cm3(Predicted) | ||||||
| Melting Point | 202-205 °C (dec.) (lit.) | ||||||
| Boling Point | 836.6±65.0 °C(Predicted) | ||||||
| Specific Rotation(α) | -85 º (c=1, DMSO) | ||||||
| Flash Point | 297.2°C | ||||||
| Solubility | Soluble in N, N-dimethylformamide, pyridine, soluble in sodium bicarbonate, sodium carbonate, sodium hydroxide and other alkaline solutions, but in the lye unstable, gradual dark brown, slightly soluble in hot glacial acetic acid, insoluble in formic acid, acetic acid, acetone, almost insoluble in water, ether, benzene, chloroform and so on. | ||||||
| Vapor Presure | 1.07E-29mmHg at 25°C | ||||||
| Appearance | Pale yellow crystalline powder | ||||||
| Color | Pale Yellow to Yellow | ||||||
| pKa | 2.72±0.70(Predicted) | ||||||
| Storage Condition | 2-8°C | ||||||
| Stability | Hygroscopic | ||||||
| Refractive Index | 1.739 | ||||||
| MDL | MFCD00134418 | ||||||
| Physical and Chemical Properties |
|
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| Use | Antibacterial, used for purging fire detoxification, hemostasis, tocolysis |
| use | baicalein has the effects of reducing cerebrovascular resistance, improving cerebral blood circulation, increasing cerebral blood flow and resisting platelet aggregation. It is clinically used for the treatment of paralysis after cerebrovascular disease. used for the treatment of infectious hepatitis, acute jaundice and chronic hepatitis, acute biliary tract infection, lead poisoning and other diseases antibacterial drugs, used for purging fire detoxification, hemostasis, fetal safety has broad-spectrum antibacterial effects, as well as choleretic, anti-inflammatory, anti-allergic, antipyretic, detoxification, diuresis, antihypertensive and other effects. It is clinically used to treat infectious hepatitis. It has a good effect on reducing glutamic pyruvic transaminase during the active period of hepatitis. It also uses leaf to treat stroke and paralysis, which can reduce cerebrovascular resistance, increase cerebral blood flow, and improve blood-brain barrier permeability And fight against platelet aggregation caused by adenosine phosphate. It can absorb ultraviolet rays, scavenge oxygen free radicals, and inhibit the production of melanin A key flavonoid found in the root of Scutellaria baicalensis has antioxidant, anti-inflammatory, anti-tumor and anti-apoptotic activities. |
| overview | baicalin is a flavonoid compound extracted and separated from scutellaria baicalensis root. it is light yellow powder at room temperature and tastes bitter. Insoluble in methanol, ethanol, acetone, slightly soluble in chloroform and nitrobenzene, almost insoluble in water, soluble in hot acetic acid. When it comes to ferric chloride, it will be green, and when it comes to lead acetate, it will produce orange precipitation. Dissolved in alkali and ammonia, it turns yellow at first, and soon turns black-brown. It has significant biological activity, with antibacterial, diuretic, anti-inflammatory, cholesterol-lowering, anti-thrombosis, asthma relief, purging fire and detoxification, hemostasis, pregnancy, anti-allergy and antispasmodic effects, and is also a specific inhibitor of mammalian liver salivary enzyme. It has the effect of regulating certain diseases and has a strong physiological effect of anti-cancer response. Mainly used for the treatment of wet temperature, summer temperature chest tightness and vomiting, damp-heat fullness, diarrhea and jaundice, lung heat cough, high fever and polydipsia, blood heat vomiting, carbuncle swelling and sore poison, fetal movement disorders. In addition, baicalin can also absorb ultraviolet rays, remove oxygen free radicals and inhibit the formation of melanin. It is a good functional cosmetic raw material. |
| source of extraction | obtained by extraction of dried roots of scutellaria (Scutellaria baicalensis Georgi), a dicotyledonous labiaceae plant. |
CAS:
21967-41-9
MF:
C21H18O11
MW:
446.36
EINECS:
606-866-1
MDL No.:
MFCD00149302
Melting point:
202-205 °C (dec.) (lit.)
alpha
-85 º (c=1, DMSO)
Boiling point:
836.6±65.0 °C(Predicted)
Density
1.737±0.06 g/cm3(Predicted)
storage temp.
2-8°C
solubility
DMSO (Slightly), Methanol (Slightly)
pka
2.72±0.70(Predicted)
form
solid
color
Pale Yellow to Yellow
optical activity
[α]20/D 85°, c = 1 in DMSO
Stability:
Hygroscopic
InChIKey
IKIIZLYTISPENI-ZFORQUDYSA-N
SMILES
OC1C(=C(O[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](C(=O)O)O2)O)C=C2OC(C3C=CC=CC=3)=CC(=O)C=12)O |&1:5,6,7,9,11,r|
LogP
1.431 (est)
Xi'an Eastling biotech Co., Ltd. is dedicated to the research and development, production, and sales of natural plant extracts; With nearly 15 years of experience in identifying, researching, developing, and producing active ingredients for medicinal plants, we focus on providing innovative products and services to customers in industries such as pharmaceuticals, health food, and cosmetics.
Eastling Biotechnology has established a global direct harvesting system for plant raw materials, ensuring the high quality and authenticity of raw materials, while also protecting the continuity and diversity of plants; Having strong research and development capabilities, we can develop more effective and specialized plant active ingredients for the pharmaceutical, health food, and cosmetics industries; We have established an advanced quality control system, and the quality control of our products depends on advanced testing instruments and high-level technical experts. The effective combination of the two forms Eastling's ability to quickly and rigorously control product quality.
We have a production system that complies with Chinese GMP and American cGMP certifications, as well as advanced and optimized large-scale industrial production technology. In addition to producing specific products for Eastling Biotechnology, we also provide customized services to meet the characteristics and needs of different customers to produce customized products.
We believe that natural active ingredients are the foundation of our service to customers. Scientific and effective production technology is the foundation for us to provide customers with specialized products. We have the ability to serve customers in the pharmaceutical, health food, and cosmetics industries, provide new product solutions, and add new value to their products.