Xi`an Eastling Biotech Co., Ltd.
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Business Type:Lab/Research institutions
Tel: +86-156-91766041
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URL: http://www.eastlingbiotech.com/
Province/state: Shaanxi
City: Xi'an city
Street: No. 201, Unit 4, Building 9, Hongqi Community, Tanjia Street, Weiyang District, Xi 'an, Shaanxi
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CAS NO.155206-00-1
98%(500-1000)Kilogram98%(100-500)Metric Ton
| Molecular Formula | C25H37NO4 | ||||||||||||||||||||||||||||
| Molar Mass | 415.57 | ||||||||||||||||||||||||||||
| Density | 1.145±0.06 g/cm3(Predicted) | ||||||||||||||||||||||||||||
| Melting Point | 66-68°C | ||||||||||||||||||||||||||||
| Boling Point | 629.8±55.0 °C(Predicted) | ||||||||||||||||||||||||||||
| Flash Point | 334.7°C | ||||||||||||||||||||||||||||
| Solubility | Soluble in ethanol (~50 mg/ml), methanol, DMSO (~25 mg/ml), DMF (~25 mg/ml), and PBS ( | ||||||||||||||||||||||||||||
| Vapor Presure | 9.94E-17mmHg at 25°C | ||||||||||||||||||||||||||||
| Appearance | Crystalline solid | ||||||||||||||||||||||||||||
| Color | White to Off-White | ||||||||||||||||||||||||||||
| pKa | 14.25±0.20(Predicted) | ||||||||||||||||||||||||||||
| Storage Condition | -20°C | ||||||||||||||||||||||||||||
| Stability | Light Sensitive | ||||||||||||||||||||||||||||
| Refractive Index | 1.591
155206-00-1 - Physico-chemical Properties
|
Open Data Verified Data
with (3aR,4R,5R,6as)-hexahydro-4-(3-oxygen -5-phenyl-1E-pentenyl) -5-(p-phenyl butyryloxy)-2H-cyclopento [B] furan -2-ketone as raw material. After reduction, the carbonyl group on the furan ring is reduced to a hydroxyl group, which is hydrolyzed and then condensed with triphenylphosphine of valeric acid to obtain 7-[(1R,2R,3R,5S)-3,5-= hydroxy 2 A [(3 S) a 5 phenyl -3-[(tetrahydro-2-H-pyran-2-yl) oxy]-1E-pentenyl] cyclopentyl]-52-heptenoic acid. Hydrolysis removes the protecting group on the hydroxyl group of the pentenyl side chain. Methyl Ester was obtained by dissolving methyl iodide in dimethylformamide under the action of Cs2 C03, and finally reacted with an aqueous solution of ethylamine to obtain the product.
Open Data Verified Data
developed by Allergan, Inc., USA, was first launched in the United States in 2001. Prostaglandin F2 a stimulator. The product selectively mimics the action of prostacyclin produced in the body, lowering intraocular pressure by increasing aqueous humor flow in the scleral pathway of the microscleral network and the pigmented layer. It is used in patients with open-angle glaucoma, or in patients with elevated intraocular pressure who are ineffective with other intraocular pressure lowering drugs (cannot reach a predetermined level of intraocular pressure after multiple measurements) or cannot tolerate.
CAS:
155206-00-1
MF:
C25H37NO4
MW:
415.57
EINECS:
642-890-9
MDL No.:
MFCD03411999
Melting point:
66-68°C
Boiling point:
629.8±55.0 °C(Predicted)
Density
1.145±0.06 g/cm3(Predicted)
storage temp.
-20°C
solubility
Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly)
pka
14.25±0.20(Predicted)
form
solid
color
White to Off-White
BCS Class
3
Stability:
Light Sensitive
InChIKey
AQOKCDNYWBIDND-FTOWTWDKSA-N
SMILES
C(NCC)(=O)CCC/C=C\C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1/C=C/[C@@H](O)CCC1=CC=CC=C1
Xi'an Eastling biotech Co., Ltd. is dedicated to the research and development, production, and sales of natural plant extracts; With nearly 15 years of experience in identifying, researching, developing, and producing active ingredients for medicinal plants, we focus on providing innovative products and services to customers in industries such as pharmaceuticals, health food, and cosmetics.
Eastling Biotechnology has established a global direct harvesting system for plant raw materials, ensuring the high quality and authenticity of raw materials, while also protecting the continuity and diversity of plants; Having strong research and development capabilities, we can develop more effective and specialized plant active ingredients for the pharmaceutical, health food, and cosmetics industries; We have established an advanced quality control system, and the quality control of our products depends on advanced testing instruments and high-level technical experts. The effective combination of the two forms Eastling's ability to quickly and rigorously control product quality.
We have a production system that complies with Chinese GMP and American cGMP certifications, as well as advanced and optimized large-scale industrial production technology. In addition to producing specific products for Eastling Biotechnology, we also provide customized services to meet the characteristics and needs of different customers to produce customized products.
We believe that natural active ingredients are the foundation of our service to customers. Scientific and effective production technology is the foundation for us to provide customers with specialized products. We have the ability to serve customers in the pharmaceutical, health food, and cosmetics industries, provide new product solutions, and add new value to their products.