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CAS NO.1428450-95-6
98%(500-1000)Kilogram98%(100-500)Metric Ton
N-(4-(2,4-Dihydroxyphenyl)thiazol-2-yl)isobutyramide
CAS: 1428450-95-6
Molecular Formula: C13H14N2O3S
| Name | N-(4-(2,4-Dihydroxyphenyl)thiazol-2-yl)isobutyramide |
| Synonyms | N-(4-(2,4-Dihydroxyphenyl)thiazol-2-yl)isobutyramide |
| CAS | 1428450-95-6 |
| Molecular Formula | C13H14N2O3S |
| Molar Mass | 278.3269 |
| Storage Condition | tem |
Thiamidol, also known as isobutyrylaminothiazolylresorcinol, is actually one of the derivatives of resorcinol.
Peptide Amritol is a patented ingredient of whiteness, which took 10 years to screen out 50000 active molecules and claims to be a strong whitening ingredient on the surface.
Why dare you make such a claim Because the confidence is too strong, the experiments conducted both invitro and in the human body have confirmed its strength.
Generally, whitening ingredients are tested for inhibiting tyrosinase activity using mushroom tyrosinase, However, the similarity between the human tyrosinase sequence and the mushroom tyrosinase sequence is only about 23%;
However, the inhibitory effect of peptide amphotericin on mushrooms is actually not very good (Figure 2) ， However, Beiersdorf's detection of human tyrosinase had a surprising finding that its inhibitory effect far exceeded other components (Figure 2) ， Calculated, it is approximately 19 times that of 4-butyl resorcinol, 85 times that of 4-hexyl resorcinol, 119 times that of 377, and 455 times that of kojic acid, surpassing arbutin by 3636 times; I really have to accept this 。
in the skin model experiment of inhibiting melanin formation, peptide amphotericin is 15 times higher than 4-butylhydroquinone and 18 times higher than hydroquinone, and it reversibly inhibits melanin production, unlike hydroquinone which is cytotoxic.
In a human clinical study, the senile plaques on the forearm of each subject were evaluated daily with 0.2% concentration of peptide amiodarone at 4, 8, and 12 weeks. It can be seen that at 12 weeks, they were almost invisible, And the surrounding skin has also turned a few degrees white
a study showed that among 50 subjects with melasma, 0.2% of peptide amphotericin improved 84% compared to 4% hydroquinone, while the latter improved 74%, The peptide amphotericin group only had mild adverse reactions, But two also developed allergic contact dermatitis.
an exploratory double-blind randomized study comparing the effects of peptide amphotericin and hydroquinone on melasma under sun protection, with the former improving 79% and the latter 61%; And the former did not show any deterioration, but the hydroquinone group had a 10% deterioration in score.
a study on post inflammation pigmentation, showed a significant decrease in pigmentation after 12 weeks of use of peptide amiodarone.
In summary, peptide amphotericin is particularly effective in inhibiting tyrosinase activity. Considering that there are multiple pathways for inhibiting melanin, the synergistic effect of combining with other different components may be better.
1. Peptide Amido is an efficient whitening agent that can be used not only for skin whitening, but also for multiple areas such as hair and eyes. It is extracted from various natural plant extracts and does not contain harmful chemicals, making it safe and reliable.
2. In vitro experimental studies have confirmed that Peptide Amido is currently the strongest known tyrosinase inhibitor, which inhibits the formation of pigments from the source, thereby achieving a strong whitening and lightening effect.
3. Multiple clinical studies have confirmed that peptide amphotericin can effectively improve mild, moderate, and severe melasma. Its therapeutic effect is similar to 4% hydroquinone and superior to 2% hydroquinone. Peptide amphotericin can also effectively improve pigmentation and senile plaques.
4. Peptide amphotericin has no cytotoxicity, is mild and non irritating, and has significant advantages over hydroquinone.
5. Using the whitening agent Peptide Amritol can effectively reduce melanin in the skin, making it fairer and smoother. Meanwhile, it can also help moisturize the skin and prevent dryness and roughness, making it an ideal skincare product.
6. In addition to being used for skin whitening, the whitening agent peptide can also be used for hair whitening. It can help restore the original white color of hair and make it brighter and smoother by inhibiting the generation of melanin in the hair.
In addition, it also has antioxidant properties, which can effectively resist the invasion of free radicals and prevent eye diseases such as eye bags and dark circles. In summary, the whitening agent Peptide Amphotericide is an efficient and safe whitening agent that can be used in various areas such as the skin, hair, and eyes. Its whitening effect is significant, and its moisturizing effect is good, which is deeply loved by users.
Xi'an Eastling biotech Co., Ltd. is dedicated to the research and development, production, and sales of natural plant extracts; With nearly 15 years of experience in identifying, researching, developing, and producing active ingredients for medicinal plants, we focus on providing innovative products and services to customers in industries such as pharmaceuticals, health food, and cosmetics.
Eastling Biotechnology has established a global direct harvesting system for plant raw materials, ensuring the high quality and authenticity of raw materials, while also protecting the continuity and diversity of plants; Having strong research and development capabilities, we can develop more effective and specialized plant active ingredients for the pharmaceutical, health food, and cosmetics industries; We have established an advanced quality control system, and the quality control of our products depends on advanced testing instruments and high-level technical experts. The effective combination of the two forms Eastling's ability to quickly and rigorously control product quality.
We have a production system that complies with Chinese GMP and American cGMP certifications, as well as advanced and optimized large-scale industrial production technology. In addition to producing specific products for Eastling Biotechnology, we also provide customized services to meet the characteristics and needs of different customers to produce customized products.
We believe that natural active ingredients are the foundation of our service to customers. Scientific and effective production technology is the foundation for us to provide customers with specialized products. We have the ability to serve customers in the pharmaceutical, health food, and cosmetics industries, provide new product solutions, and add new value to their products.