Xi`an Eastling Biotech Co., Ltd.
Diamond Supplier
- Diamond
Supplier - 1st
years
Diamond Supplier
Product Certification&
Enterprise Certification
Country: 
China (Mainland)
Business Type:Lab/Research institutions
Tel: +86-156-91766041
Mobile:
Tel: +86-156-91766041
Fax:
URL: http://www.eastlingbiotech.com/
Province/state: Shaanxi
City: Xi'an city
Street: No. 201, Unit 4, Building 9, Hongqi Community, Tanjia Street, Weiyang District, Xi 'an, Shaanxi
MaxCard:
Contact Suppliers
CAS NO.135463-81-9
98%(500-1000)Kilogram98%(100-500)Metric Ton
Coluracetam
CAS: 135463-81-9
Molecular Formula: C19H23N3O3
| Name | Coluracetam |
| Synonyms | BCI-540 Coluracetam COLURACETAM Coluracetam, MKC-231 1-Pyrrolidineacetamide,2-oxo-N-(5,6,7,8-tetrahydro-2,3-dimethylfuro[2,3-b]quinolin-4-yl)- 2-oxo-N-(5,6,7,8-tetrahydro-2,3-dimethyl-furo[2,3-b]quinolin-4-yl)-1-pyrrolidineacetamide N-(2,3-Dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2-oxopyrrolidin-1-yl)acetamide 1-[N-(2,3-DiMethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)carbaMoylMethyl]pyrrolidin-2-one |
| CAS | 135463-81-9 |
| EINECS | 1308068-626-2 |
| InChI | InChI=1/C19H23N3O3/c1-11-12(2)25-19-17(11)18(13-6-3-4-7-14(13)20-19)21-15(23)10-22-9-5-8-16(22)24/h3-10H2,1-2H3,(H,20,21,23) |
| Molecular Formula | C19H23N3O3 |
| Molar Mass | 341.404 |
| Density | 1.291g/cm3 |
| Boling Point | 634.1°C at 760 mmHg |
| Flash Point | 337.3°C |
| Vapor Presure | 5.54E-16mmHg at 25°C |
| Storage Condition | Room Temprature |
| Refractive Index | 1.64 |
| Physical and Chemical Properties | Storage conditions Sealed in dry,Room Temperature acidity coefficient (pKa) 12.01±0.20(Predicted) |
The chemical name of koalacetam (Coluracetam) is N-(2, 3-dimethyl-5, 6,7, 8-tetrahydrofurano [2,3-b] quinolin-4-yl)-2-(2-oxopyrrolidin-1-yl) acetamide, which is a type of cettam drug under development, belongs to the cetam derivative. Sytam drugs are widely used in the clinical treatment of cognitive dysfunction and epilepsy due to their unique mechanism of action, remarkable curative effect and extremely low toxicity. The variety is still in clinical trials.
density: 1.291g/cm3
Boiling point: 634.1°C at 760 mmHg
Flash point: 337.3°C
Refractive index: 1.64
Vapor pressure: 5.54 E-16mmHg at 25°C
By participating in the HACU process, koalacetam increases the activity of cholinergic neurons by increasing the rate-limiting step of synaptic intake of cholinergic neurotransmitter acetylcholine, and has the ability to improve cognition.
1. for nootropic drugs. It can be used to treat memory and intellectual disorders caused by senile dementia, mild to moderate vascular dementia, trauma and other diseases, and to promote children's intellectual development.
2. Antidepressant effect. By promoting the transmission of nerve signals, it has a significant effect on depression
Coluracetam (BCI-540, MKC-231) is a puzzle drug with cognitive and neuroprotective effects.
Mol Download Chemical properties
CAS:
135463-81-9
MF:
C19H23N3O3
MW:
341.4
EINECS:
1308068-626-2
MDL No.:
MFCD00901416
Boiling point:
634.1±55.0 °C(Predicted)
Density
1.291±0.06 g/cm3(Predicted)
storage temp.
Sealed in dry,Room Temperature
solubility
DMF: 1 mg/ml; DMSO: 2 mg/ml; Ethanol: 2 mg/ml; PBS (pH 7.2): insol
pka
12.01±0.20(Predicted)
form
A crystalline solid
InChI
InChI=1S/C19H23N3O3/c1-11-12(2)25-19-17(11)18(13-6-3-4-7-14(13)20-19)21-15(23)10-22-9-5-8-16(22)24/h3-10H2,1-2H3,(H,20,21,23)
InChIKey
PSPGQHXMUKWNDI-UHFFFAOYSA-N
SMILES
N1(CC(NC2C3=C(N=C4OC(C)=C(C)C4=2)CCCC3)=O)CCCC1=O
Xi'an Eastling biotech Co., Ltd. is dedicated to the research and development, production, and sales of natural plant extracts; With nearly 15 years of experience in identifying, researching, developing, and producing active ingredients for medicinal plants, we focus on providing innovative products and services to customers in industries such as pharmaceuticals, health food, and cosmetics.
Eastling Biotechnology has established a global direct harvesting system for plant raw materials, ensuring the high quality and authenticity of raw materials, while also protecting the continuity and diversity of plants; Having strong research and development capabilities, we can develop more effective and specialized plant active ingredients for the pharmaceutical, health food, and cosmetics industries; We have established an advanced quality control system, and the quality control of our products depends on advanced testing instruments and high-level technical experts. The effective combination of the two forms Eastling's ability to quickly and rigorously control product quality.
We have a production system that complies with Chinese GMP and American cGMP certifications, as well as advanced and optimized large-scale industrial production technology. In addition to producing specific products for Eastling Biotechnology, we also provide customized services to meet the characteristics and needs of different customers to produce customized products.
We believe that natural active ingredients are the foundation of our service to customers. Scientific and effective production technology is the foundation for us to provide customers with specialized products. We have the ability to serve customers in the pharmaceutical, health food, and cosmetics industries, provide new product solutions, and add new value to their products.