Xi`an Eastling Biotech Co., Ltd.
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Tel: +86-156-91766041
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Province/state: Shaanxi
City: Xi'an city
Street: No. 201, Unit 4, Building 9, Hongqi Community, Tanjia Street, Weiyang District, Xi 'an, Shaanxi
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CAS NO.13292-46-1
98%(500-1000)Kilogram98%(100-500)Metric Ton
| Molecular Formula | C43H58N4O12 |
| Molar Mass | 822.94 |
| Density | 1.1782 (rough estimate) |
| Melting Point | 183°C (dec.) |
| Boling Point | 761.02°C (rough estimate) |
| Flash Point | 520.7°C |
| Water Solubility | Soluble in DMSO or methanolSoluble in water, ethyl acetate, chloroform, methanol, tetrahydrofuran and dimethyl sulfoxide. |
| Solubility | H2O: 1.3 mg/mL (pH 4.3);DMSO: 100 mg/mL;H2O: 2.5 mg/mL at 25°C (pH 7.3). Easily soluble in chloroform, ethyl acetate, methanol, |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | faintly orange to red-brown(powder) |
| Color | faint red to very dark red |
| Merck | 14,8216 |
| BRN | 5723476 |
| pKa | 1.7, 7.9(at 25℃) |
| Storage Condition | 2-8°C |
| Stability | Hygroscopic, Light Sensitive |
| Refractive Index | 1.6000 (estimate) |
| MDL | MFCD00151389 |
| Physical and Chemical Properties | Melting point 183°C (dec.) |
| Use | Has a broad-spectrum antibacterial effect, gram-positive cocci, Mycobacterium tuberculosis has good antibacterial activity, the same antibacterial spectrum and rifampicin |
| use | broad-spectrum antibiotics. It has antibacterial or bactericidal effects on Mycobacterium tuberculosis, Gram-positive bacteria and some Gram-cloudy bacteria. It is mainly used for the infection of drug-resistant tuberculosis and drug-resistant Staphylococcus aureus, and has certain curative effect on leprosy. is a broad-spectrum antibiotic, and can enter the cell, is a full-effect bactericidal drug, bactericidal power is a broad-spectrum antibiotic, on the differences of bacilli and gram positive, negative bacteria have strong bactericidal effect used as pharmaceutical intermediates broad-spectrum antibiotics. It has antibacterial or bactericidal effects on Mycobacterium tuberculosis, Gram-positive bacteria and some Gram-cloudy bacteria. It is mainly used for the infection of drug-resistant tuberculosis and drug-resistant Staphylococcus aureus, and has certain curative effect on leprosy. It is a broad-spectrum antibiotic and can enter the cell. It is a full-effect bactericidal drug with strong bactericidal power. It is a broad-spectrum antibiotic. It has a strong bactericidal effect on divergent bacilli and gram-positive and negative bacteria. It has a broad-spectrum antibacterial effect as a pharmaceutical intermediate. It has good antibacterial activity against Gram-positive cocci and Mycobacterium tuberculosis. The antibacterial spectrum is the same as rifampicin. The use has a broad-spectrum antibacterial effect, it has good antibacterial activity against Gram-positive cocci and Mycobacterium tuberculosis, and the antibacterial spectrum is the same as rifampicin raw materials (anti-tuberculosis antibiotics) inhibit DNA recombination and protein insertion into mature virus particles. Inhibit the initiation of RNA synthesis by binding to the β-subunit of RNA polymerase. |
| Production method | Rifampicin is a semi-synthetic derivative of rifamycin SV. Rifamycin SV is oxidized to rifamycin S, and then formylated with formaldehyde and tert-butylamine to generate 3-formyl tert-butylamine rifamycin S, which is then reduced with vitamin C and condensed with 1-Methyl -4-aminopiperazine to get rifampicin. |
CAS:
13292-46-1
MF:
C43H58N4O12
MW:
822.94
EINECS:
236-312-0
MDL No.:
MFCD00151389
Melting point:
183°C (dec.)
Boiling point:
761.02°C (rough estimate)
Density
1.1782 (rough estimate)
refractive index
1.6000 (estimate)
storage temp.
2-8°C
solubility
chloroform: soluble50mg/mL, clear
pka
1.7, 7.9(at 25℃)
form
crystalline
color
faint red to very dark red
Water Solubility
Soluble in DMSO or methanolSoluble in water, ethyl acetate, chloroform, methanol, tetrahydrofuran and dimethyl sulfoxide.
Merck
14,8216
BRN
5723476
BCS Class
2
Stability:
Hygroscopic, Light Sensitive
Xi'an Eastling biotech Co., Ltd. is dedicated to the research and development, production, and sales of natural plant extracts; With nearly 15 years of experience in identifying, researching, developing, and producing active ingredients for medicinal plants, we focus on providing innovative products and services to customers in industries such as pharmaceuticals, health food, and cosmetics.
Eastling Biotechnology has established a global direct harvesting system for plant raw materials, ensuring the high quality and authenticity of raw materials, while also protecting the continuity and diversity of plants; Having strong research and development capabilities, we can develop more effective and specialized plant active ingredients for the pharmaceutical, health food, and cosmetics industries; We have established an advanced quality control system, and the quality control of our products depends on advanced testing instruments and high-level technical experts. The effective combination of the two forms Eastling's ability to quickly and rigorously control product quality.
We have a production system that complies with Chinese GMP and American cGMP certifications, as well as advanced and optimized large-scale industrial production technology. In addition to producing specific products for Eastling Biotechnology, we also provide customized services to meet the characteristics and needs of different customers to produce customized products.
We believe that natural active ingredients are the foundation of our service to customers. Scientific and effective production technology is the foundation for us to provide customers with specialized products. We have the ability to serve customers in the pharmaceutical, health food, and cosmetics industries, provide new product solutions, and add new value to their products.