Xi`an Eastling Biotech Co., Ltd.
Diamond Supplier
- Diamond
Supplier - 1st
years
Diamond Supplier
Product Certification&
Enterprise Certification
Country: 
China (Mainland)
Business Type:Lab/Research institutions
Tel: +86-156-91766041
Mobile:
Tel: +86-156-91766041
Fax:
URL: http://www.eastlingbiotech.com/
Province/state: Shaanxi
City: Xi'an city
Street: No. 201, Unit 4, Building 9, Hongqi Community, Tanjia Street, Weiyang District, Xi 'an, Shaanxi
MaxCard:
Contact Suppliers
CAS NO.94-62-2
98%(1-25)Kilogram98%(26-500)Kilogram98%(501-1000)Kilogram
Piperine
CAS: 94-62-2
Molecular Formula: C17H19NO3
| Name | Piperine |
| Synonyms | PIPERINE Piperine FEMA 2909 Bioperine 1-Piperylpiperidine 1-PIPERYLPIPERIDINE N-PIPEROYLPIPERIDIN 1-PIPEROYLPIPERIDINE 1-PIPERONYLPIPERIDINE 5-BENZO[1,3]DIOXOL-5-YL-1-PIPERIDIN-1-YL-PENTA-2,4-DIEN-1-ONE 5-(1,3-benzodioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one (E,E)-1-[5-(1,3-Benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]-piperidine (2E,4Z)-5-(1,3-benzodioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one (2E,4E)-5-(1,3-benzodioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one |
| CAS | 94-62-2 |
| EINECS | 202-348-0 |
| InChI | InChI=1/C17H19NO3/c19-17(18-10-4-1-5-11-18)7-3-2-6-14-8-9-15-16(12-14)21-13-20-15/h2-3,6-9,12H,1,4-5,10-11,13H2/b6-2-,7-3+ |
| InChIKey | MXXWOMGUGJBKIW-YPCIICBESA-N |
| Molecular Formula | C17H19NO3 |
| Molar Mass | 285.34 |
| Density | 1.0864 (rough estimate) |
| Melting Point | 131-135°C(lit.) |
| Boling Point | 427.77°C (rough estimate) |
| Flash Point | 255.298°C |
| JECFA Number | 1600 |
| Water Solubility | 40 mg/L (18 ºC) |
| Solubility | Soluble in acetic acid, benzene, ethanol and chloroform, slightly soluble in ether. |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | White crystal powder |
| Color | Off-white to tan or yellow-tan |
| Merck | 14,7472 |
| BRN | 90741 |
| pKa | 12.22(at 18℃) |
| Storage Condition | Sealed in dry,Room Temperature |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Sensitive | `sensitive` to light, humidity and air |
| Refractive Index | 1.5400 (estimate) |
| MDL | MFCD00005839 |
| Physical and Chemical Properties | Soluble in acetic acid, benzene, ethanol and chloroform, slightly soluble in ether. Dry near-ripening or ripening fruit derived from Piper nigrum L., a Piperaceae plant. |
| Risk Codes | R22 - Harmful if swallowed R21/22 - Harmful in contact with skin and if swallowed. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37 - Wear suitable protective clothing and gloves. S36 - Wear suitable protective clothing. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
| UN IDs | UN 3077 9 / PGIII |
| Introduction | Piperine is a broad-spectrum anticonvulsant, which has a good antagonistic effect on experimental electroconvulsions in mice, the pentylenetetrazol, Tetrandrine toxin, strychnine, as well as intracerebroventricular injection of cortiine, glutamic acid caused by seizures and auditory seizures, have different degrees of antagonism. Clinical trials, for certain types of epilepsy also have curative effect. A folk prescription "white pepper plus radish" for the treatment of epilepsy is provided in the state, and the piperine analog 3-(3,4-methylenedioxyphenyl) with simplified structure is synthesized artificially. Acryloyl piperidine (trade name antiepileptic spirit). The toxicity of piperine to flies was higher than that of pyrethrum. |
| pharmacological effects | pepper is the most basic ingredient in Indian medicine and is used to treat many diseases. Pharmacological studies have proved that many of their traditional efficacy, such as: analgesic and antipyretic effects, antioxidant effects, antibacterial effects, etc., Piperine is the active ingredient of pepper. Piperine has a wide range of pharmacological effects, and has been found to have antioxidant, immunomodulatory, anti-tumor effects. |
| Use | for content determination/identification/pharmacological experiments. Pharmacological effects: Piperine is a broad-spectrum anticonvulsant drug, experimental electroconvulsions in mice have a good antagonistic effect on pentylenetetrazol, Tetrandrine toxin, strychnine, as well as intracerebroventricular injection tube, seizures caused by glutamate and auditory seizures, have different degrees of antagonism. It is also effective for some types of epilepsy. The toxicity of piperine to flies is higher than that of pyrethrum. |
| category | pesticide |
| toxicity grade | high toxicity |
| Acute toxicity | oral-rat LD50: 514 mg/kg; Oral-mouse LD50: 330 mg/kg |
| flammability hazard characteristics | toxic NOx gases from combustion |
| storage and transportation characteristics | The warehouse is ventilated and dried at low temperature; It is stored and transported separately from food raw materials |
| extinguishing agent | dry powder, foam, sand |
Mol Download Chemical properties
CAS:
94-62-2
MF:
C17H19NO3
MW:
285.34
EINECS:
202-348-0
MDL No.:
MFCD00005839
Melting point:
131-135 °C(lit.)
Boiling point:
427.77°C (rough estimate)
Density
1.0864 (rough estimate)
FEMA
refractive index
1.5400 (estimate)
storage temp.
Sealed in dry,Room Temperature
solubility
0.04g/l
pka
12.22(at 18℃)
form
Crystalline Powder
color
Off-white to tan or yellow-tan
Odor
at 1.00 % in propylene glycol. pepper animal
Odor Type
spicy
Water Solubility
40 mg/L (18 ºC)
Merck
14,7472
JECFA Number
1600
BRN
90741
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
MXXWOMGUGJBKIW-YPCIICBESA-N
LogP
2.66
Xi'an Eastling biotech Co., Ltd. is dedicated to the research and development, production, and sales of natural plant extracts; With nearly 15 years of experience in identifying, researching, developing, and producing active ingredients for medicinal plants, we focus on providing innovative products and services to customers in industries such as pharmaceuticals, health food, and cosmetics.
Eastling Biotechnology has established a global direct harvesting system for plant raw materials, ensuring the high quality and authenticity of raw materials, while also protecting the continuity and diversity of plants; Having strong research and development capabilities, we can develop more effective and specialized plant active ingredients for the pharmaceutical, health food, and cosmetics industries; We have established an advanced quality control system, and the quality control of our products depends on advanced testing instruments and high-level technical experts. The effective combination of the two forms Eastling's ability to quickly and rigorously control product quality.
We have a production system that complies with Chinese GMP and American cGMP certifications, as well as advanced and optimized large-scale industrial production technology. In addition to producing specific products for Eastling Biotechnology, we also provide customized services to meet the characteristics and needs of different customers to produce customized products.
We believe that natural active ingredients are the foundation of our service to customers. Scientific and effective production technology is the foundation for us to provide customers with specialized products. We have the ability to serve customers in the pharmaceutical, health food, and cosmetics industries, provide new product solutions, and add new value to their products.