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CAS NO.56-69-9
98%(1-25)Kilogram98%(26-500)Kilogram98%(501-1000)Kilogram
DL-5-Hydroxytryptophan
CAS: 56-69-9;114-03-4
Molecular Formula: C11H12N2O3
| Name | DL-5-Hydroxytryptophan |
| Synonyms | 5-HTP DL-5-HTP H-Trp(5-OH)-OH HYDROXYTRYPTOPHAN 5-hydroxytrytophan 5-hydroxytryptophan DL-5-Hydroxytryptophan 5-hydroxy-D-tryptophan DL-5-HYDROXYTRYPTOPHAN 5-HYDROXY-DL-TRYPTOPHAN 5-Hydroxy-DL-tryptophan 5-Hydroxytryptophan(5-HTP) 5-HTP (Griffonia Seeds P.E.) 5-hydroxy-dl-tryptophan crystalline DL-2-AMINO-3-(5-HYDROXYINDOLYL)PROPIONIC ACID DL-2-Amino-3-[3-(5-hydroxyindole)]propionic acid 2-Amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid DL-2-Amino-3-(5-hydroxyindolyl)propionic acid, DL-5-HTP |
| CAS | 56-69-9 114-03-4 |
| EINECS | 200-284-8 |
| InChI | InChI=1/C11H12N2O3/c12-9(11(15)16)3-6-5-13-10-2-1-7(14)4-8(6)10/h1-2,4-5,9,13-14H,3,12H2,(H,15,16)/t9-/m0/s1 |
| InChIKey | LDCYZAJDBXYCGN-UHFFFAOYSA-N |
| Molecular Formula | C11H12N2O3 |
| Molar Mass | 220.22 |
| Density | 1.484 |
| Melting Point | 298-300°C |
| Boling Point | 361.16°C (rough estimate) |
| Specific Rotation(α) | -30.9~-34.7° |
| Flash Point | 268.7°C |
| Water Solubility | Soluble in water (4 mg/ml at 25°C), methanol. |
| Solubility | Soluble in water |
| Vapor Presure | 1.15E-11mmHg at 25°C |
| Appearance | White powder |
| Color | Off-White to Pale Beige |
| Merck | 14,4847 |
| BRN | 88199 |
| pKa | 2.22±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.5200 (estimate) |
| MDL | MFCD00005651 |
| Physical and Chemical Properties | Light gray powder, soluble in methanol, ethanol, DMSO and other organic solvents, from Africa Ghana seed. |
| Use | Used as a Biochemical reagent |
| In vitro study | 5-Hydroxytryptophan (5-HTP) is an intermediate in the biosynthesis of serotonin by the essential amino acid L-tryptophan (LT). It is able to easily cross the blood-brain barrier and effectively increases serotonin synthesis in the central nervous system (CNS). 5-HTP administration has been shown to be effective in treating a variety of conditions, including depression, fibromyalgia, obesity due to overeating, chronic headaches, and insomnia. Clinical evidence suggests that 5-Hydroxytryptophan provides better relief of depression than placebo. |
| In vivo study | LD50: Mouse 1800 mg/kg (I. g.); Rat 300 mg/kg (I. g.) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| properties | light gray-white fine powder with slight gas and slightly salty taste. |
| mechanism of action | 5-hydroxytryptophan is the precursor of human serotonin, can help the body balance this hormone to control the body's mood, improve sleep quality, and can effectively control appetite, improve the sensitivity of the satiety center, in the process of weight loss diet control, reduce hunger, make the weight loss process easier and easier to achieve. |
| biological activity | 5-hydroxytrophophan (5-HTP, NSC-92523), in the presence of Vitamin B6, the enzyme aromatic-L-amino acid decarboxylase is decarboxylated to serotonin (5-hydroxytryptamine or 5-HT). |
| Use | use as a Biochemical reagent 1. Anti-depression: 5-HTP is a metabolite of the amino acid tryptophan, it is the precursor of human serotonin and is used to synthesize serotonin (an important substance that plays a role in the function of common nerves and brain). Helps with normal nerve material and brain function and can treat depression. 2, relieve stress and improve sleep: can help the body balance this hormone to control the body's mood, improve sleep quality, can effectively inhibit pain, thus 5-hydroxytryptophan was also used to treat Sleep Initiation and Maintenance Disorders. |
Mol Download Chemical properties
CAS:
56-69-9
MF:
C11H12N2O3
MW:
220.22
EINECS:
200-284-8
MDL No.:
MFCD00005651
Melting point:
298-300°C
Boiling point:
361.16°C (rough estimate)
Density
1.484
refractive index
1.5200 (estimate)
storage temp.
Keep in dark place,Sealed in dry,Room Temperature
solubility
DMSO (Slightly), Methanol (Slightly)
pka
2.22±0.10(Predicted)
form
solid
color
Off-White to Pale Beige
Water Solubility
Soluble in water (4 mg/ml at 25°C), methanol.
Merck
14,4847
BRN
88199
InChIKey
LDCYZAJDBXYCGN-UHFFFAOYSA-N
LogP
-0.292 (est)
Xi'an Eastling biotech Co., Ltd. is dedicated to the research and development, production, and sales of natural plant extracts; With nearly 15 years of experience in identifying, researching, developing, and producing active ingredients for medicinal plants, we focus on providing innovative products and services to customers in industries such as pharmaceuticals, health food, and cosmetics.
Eastling Biotechnology has established a global direct harvesting system for plant raw materials, ensuring the high quality and authenticity of raw materials, while also protecting the continuity and diversity of plants; Having strong research and development capabilities, we can develop more effective and specialized plant active ingredients for the pharmaceutical, health food, and cosmetics industries; We have established an advanced quality control system, and the quality control of our products depends on advanced testing instruments and high-level technical experts. The effective combination of the two forms Eastling's ability to quickly and rigorously control product quality.
We have a production system that complies with Chinese GMP and American cGMP certifications, as well as advanced and optimized large-scale industrial production technology. In addition to producing specific products for Eastling Biotechnology, we also provide customized services to meet the characteristics and needs of different customers to produce customized products.
We believe that natural active ingredients are the foundation of our service to customers. Scientific and effective production technology is the foundation for us to provide customers with specialized products. We have the ability to serve customers in the pharmaceutical, health food, and cosmetics industries, provide new product solutions, and add new value to their products.