Xi`an Eastling Biotech Co., Ltd.
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City: Xi'an city
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CAS NO.41451-87-0
98%(1-25)Kilogram98%(26-500)Kilogram98%(501-1000)Kilogram
CAS: 41451-87-0
Molecular Formula: C27H44O8
| Molecular Formula | C27H44O8 |
| Molar Mass | 496.63 |
| Density | 1.33 |
| Melting Point | 166-170°C |
| Boling Point | 740.1±60.0 °C(Predicted) |
| Specific Rotation(α) | +52 (c, 1.46 in MeOH) |
| Flash Point | 415.3°C |
| Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents |
| Vapor Presure | 2.79E-25mmHg at 25°C |
| Appearance | Powder |
| Color | Off-White to Pale Yellow |
| pKa | 13.84±0.70(Predicted) |
| Storage Condition | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| Refractive Index | 1.609 |
| MDL | MFCD04307740 |
| In vitro study | The ability of Turkesterone to displace [ 3 H]ponA from in vitro-expressed DmEcR/DmUSP receptor complex is assessed. The EC 50 is 0.8 μM in the B II bioassay, K i value is 90 nM in the receptor assay. |
| effect | dew grass (CyanotisarachnoideaC.B.Clarke), also known as pearl dew grass, chicken crown ginseng, etc., is a perennial herb of the genus Lanergrass of the Duckweed family. It is widely distributed in Yunnan Province. It has the effects of replenishing deficiency, dehumidification, relaxing muscles and activating collaterals. Tukesterone was isolated from this plant for the first time. |
| preparation | dew grass (2.5kg) is heated and refluxed with 75% ethanol to recover ethanol to obtain concentrated solution. Extraction with ethyl acetate and n-butanol; Take the ethyl acetate extract, conduct Al2O3 (neutral) column chromatography, elute with chloroform-methanol gradient, chloroform-methanol (4:1) elution part is recrystallized with ethyl acetate-methanol to obtain compound 3(200mg); The 3: 1 elution part is prepared by thin layer chromatography (stationary phase: silica gel GF254; Mobile phase: chloroform-methanol = 5: 1) to obtain compound 1(10mg); The methanol elution part was separated by preparative high performance liquid chromatography (ODS, methanol/water = 31: 69,242nm detection) to obtain tukesterone (5mg). |
| Biological activity | Turkesterone isolated from Ajuga turkestanica, Turkesterone is an effective ecdysone used as ecdysteroid receptor (EcR) agonist in some insect systems. |
| target | Ecdysteroid receptor (EcR) |
Mol Download Chemical properties
CAS:
41451-87-0
MF:
C27H44O8
MW:
496.63
EINECS:
000-000-0
MDL No.:
MFCD04307740
Melting point:
166-170°C
Boiling point:
740.1±60.0 °C(Predicted)
Density
1.33
storage temp.
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility
DMSO (Slightly), Methanol (Slightly)
pka
13.84±0.70(Predicted)
form
Solid
color
Off-White to Pale Yellow
Water Solubility
insoluble in water
Stability:
Hygroscopic
Xi'an Eastling biotech Co., Ltd. is dedicated to the research and development, production, and sales of natural plant extracts; With nearly 15 years of experience in identifying, researching, developing, and producing active ingredients for medicinal plants, we focus on providing innovative products and services to customers in industries such as pharmaceuticals, health food, and cosmetics.
Eastling Biotechnology has established a global direct harvesting system for plant raw materials, ensuring the high quality and authenticity of raw materials, while also protecting the continuity and diversity of plants; Having strong research and development capabilities, we can develop more effective and specialized plant active ingredients for the pharmaceutical, health food, and cosmetics industries; We have established an advanced quality control system, and the quality control of our products depends on advanced testing instruments and high-level technical experts. The effective combination of the two forms Eastling's ability to quickly and rigorously control product quality.
We have a production system that complies with Chinese GMP and American cGMP certifications, as well as advanced and optimized large-scale industrial production technology. In addition to producing specific products for Eastling Biotechnology, we also provide customized services to meet the characteristics and needs of different customers to produce customized products.
We believe that natural active ingredients are the foundation of our service to customers. Scientific and effective production technology is the foundation for us to provide customers with specialized products. We have the ability to serve customers in the pharmaceutical, health food, and cosmetics industries, provide new product solutions, and add new value to their products.