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Xi`an Eastling Biotech Co., Ltd.

Country: China (Mainland)

Business Type:Lab/Research institutions

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Tel: +86-156-91766041

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URL: http://www.eastlingbiotech.com/

Province/state: Shaanxi

City: Xi'an city

Street: No. 201, Unit 4, Building 9, Hongqi Community, Tanjia Street, Weiyang District, Xi 'an, Shaanxi

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Factory high quality Dipyridamole

CAS NO.58-32-2

  • FOB Price: USD: 6.00-7.00 /Kilogram Get Latest Price
  • Min.Order: 1 Gram
  • Payment Terms: L/C,T/T,MoneyGram,Other
  • Available Specifications:

    98%(500-1000)Kilogram98%(100-500)Metric Ton

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Product Details

Keywords

  • Dipyridamole
  • 58-32-2
  • Dipyridamole powder

Quick Details

  • ProName: Factory high quality Dipyridamole
  • CasNo: 58-32-2
  • Molecular Formula: C60H86N16O13
  • Appearance: white powder
  • Application: Dietary supplements;Food;Additives;Pha...
  • DeliveryTime: 7
  • PackAge: 1kg/bag,5kg/bag,25kg/drum
  • Port: any port in china
  • ProductionCapacity: 1 Kilogram/Day
  • Purity: purity 98%-101%
  • Storage: 20℃
  • Transportation: low temp
  • LimitNum: 1 Gram
  • Related Substances: 1
  • Residue on Ignition: 1
  • Heavy Metal: 1
  • Valid Period: 1

Superiority

Dipyridamole

CAS: 58-32-2

Molecular Formula: C24H40N8O4

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58-32-2 - Names and Identifiers

Name Dipyridamole
Synonyms Coroxin
Corosan
Curantyl
Dipyridan
Dipiridamol
Dipyridamole
Dypyridamole
Dipyridamine
Dipyridamole (FDA)
Dipyridamole (200 mg)
2,2,2,2-(4,8-dipiperidinopyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilotetraethanol
1,1',1'',1'''-{[4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidine-2,6-diyl]dinitrilo}tetraethanol
2,2',2'',2'''-((4,8-Di(piperidin-1-yl)pyrimido[5,4-d]-pyrimidine-2,6-diyl)bis(azanetriyl))tetraet
CAS 58-32-2
EINECS 200-374-7
InChI InChI=1/C24H40N8O4/c1-15(33)31(16(2)34)23-25-19-20(21(27-23)29-11-7-5-8-12-29)26-24(32(17(3)35)18(4)36)28-22(19)30-13-9-6-10-14-30/h15-18,33-36H,5-14H2,1-4H3

58-32-2 - Physico-chemical Properties

Molecular Formula C24H40N8O4
Molar Mass 504.63
Density 1.2046 (rough estimate)
Melting Point 165-166 °C (lit.)
Boling Point 593.96°C (rough estimate)
Flash Point 396.09°C
Water Solubility Soluble in chloroform, methanol, dilute acids, ethanol. Slightly soluble in water.
Solubility DMSO 101 mg/mL;Water <1 mg/mL;Ethanol 50 mg/mL. Easily soluble in methanol, ethanol, chloroform, soluble in dilute acid below pH3.3, not very soluble in acetone, benzene, ethyl acetate, slightly soluble in water. The solution is
Vapor Presure 0mmHg at 25°C
Appearance Yellow powder
Color yellow
Merck 14,3346
pKa pKa 6.4 (Uncertain)
Storage Condition room temp
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Refractive Index 1.6910 (estimate)
MDL MFCD00010555
Physical and Chemical Properties Yellow crystalline powder. Melting point of 163 ° C, soluble in chloroform and dilute acid, soluble in ethanol, acetone-soluble, almost insoluble in water. No odor, slightly bitter taste.
Use Anti-platelet aggregation drug, coronary artery dilator, for the prevention of recurrence of myocardial infarction and angina pectoris

 

chlorine-containing compounds

take about 20mg of this product, according to the oxygen flask combustion method (General rule 0703) for organic damage, 0.4% sodium hydroxide solution 20ml as the absorption liquid, once the combustion is completed, strong shaking for 15 minutes, add 10ml of dilute nitric acid, move to 50ml Nessler's colorimetric tube, check according to the chloride inspection method (General 0801), and operate with the control solution (the same method as the test sample), however, the test article is not contained in the filter paper during combustion, and 4.0 of standard sodium chloride solution is added), and it should not be more concentrated (0.20%).

Related substances

take this product, add methanol to dissolve and dilute to make 1.0 mg of the solution was used as a test solution, and an appropriate amount was quantitatively diluted with methanol to prepare a solution containing 10ug per 1 ml as a control solution. According to the high performance liquid chromatography (General rule 0512) test, with eighteen alkyl silane bonded silica gel as filler; Disodium hydrogen phosphate solution [take disodium hydrogen phosphate 250mg, add water 250ml, dissolve, Dropwise add phosphoric acid solution (1-3) the pH value was adjusted to 4.6]-methanol (25:75) as the mobile phase; The detection wavelength was 288nm, and the number of theoretical plates was not less than 600 based on the dipyridamole peak. The LOLs of the test solution and the control solution were respectively injected into the human liquid chromatograph, and the chromatogram was recorded to 2 times of the retention time of the main component peak. If there are impurity peaks in the chromatogram of the test solution, the sum of each impurity peak area shall not be greater than the main peak area of the control solution (1.0%).

residual solvent

take about 0.1g of this product, precision weighing, in the top empty bottle, Precision Add 5ml of N,IV-dimethylformamide to dissolve, seal, as a test solution; Separately take methanol, appropriate amount of acetone and ethyl acetate, precision weighing, quantitative dilution with N,N-dimethylformamide to make solution containing about 50ug in each lml, precision measuring 5ml, in the empty bottle, sealed, as a control solution. Test as residual solvent assay (General 0861 second method). With 6% cyanopropylphenyl-94% dimethylpolysiloxane (or polar similar) as the stationary liquid; The initial temperature is 50°C, maintained for 3 minutes, and the temperature is raised to 160°C at a rate of 40°C per minute, maintained for 3 minutes; the inlet temperature was 200°C; The detector temperature was 250°C; The headspace bottle equilibrium temperature was 80°C and the equilibrium time was 30 minutes. Take the reference solution into the headspace, the separation degree between the peaks of each component shall meet the requirements. Then the sample solution and the reference solution were injected with headspace, and the chromatogram was recorded. According to the external standard method to calculate the peak area, methanol, acetone and ethyl acetate residues should be in accordance with the provisions.

loss on drying

take this product, dry to constant weight at 105°C, weight loss shall not exceed 0.5% (General rule 0831).

ignition residue

take l.Og of this product and check it according to law (General rule 0841). The residue left shall not exceed 0.1%.

Heavy metals

The residue left under the item of taking the ignition residue shall not contain more than 10 parts per million of heavy metal when examined by law (General Principles 0821, Law II).

Details

Dipyridamole

 

CAS:

58-32-2

MF:

C24H40N8O4

MW:

504.63

EINECS:

200-374-7

MDL No.:

MFCD00010555

Properties

Melting point:

165-166 °C (lit.)

Boiling point:

593.96°C (rough estimate)

Density 

1.2046 (rough estimate)

refractive index 

1.6910 (estimate)

storage temp. 

room temp

solubility 

DMSO: soluble

form 

powder

pka

pKa 6.4 (Uncertain)

color 

yellow

Water Solubility 

Soluble in chloroform, methanol, dilute acids, ethanol. Slightly soluble in water.

Merck 

14,3346

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Xi'an Eastling biotech Co., Ltd. is dedicated to the research and development, production, and sales of natural plant extracts; With nearly 15 years of experience in identifying, researching, developing, and producing active ingredients for medicinal plants, we focus on providing innovative products and services to customers in industries such as pharmaceuticals, health food, and cosmetics.

 

Eastling Biotechnology has established a global direct harvesting system for plant raw materials, ensuring the high quality and authenticity of raw materials, while also protecting the continuity and diversity of plants; Having strong research and development capabilities, we can develop more effective and specialized plant active ingredients for the pharmaceutical, health food, and cosmetics industries; We have established an advanced quality control system, and the quality control of our products depends on advanced testing instruments and high-level technical experts. The effective combination of the two forms Eastling's ability to quickly and rigorously control product quality.

 

We have a production system that complies with Chinese GMP and American cGMP certifications, as well as advanced and optimized large-scale industrial production technology. In addition to producing specific products for Eastling Biotechnology, we also provide customized services to meet the characteristics and needs of different customers to produce customized products.

We believe that natural active ingredients are the foundation of our service to customers. Scientific and effective production technology is the foundation for us to provide customers with specialized products. We have the ability to serve customers in the pharmaceutical, health food, and cosmetics industries, provide new product solutions, and add new value to their products.